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Database: UniProt
Entry: A0A0D2KIC8_9EURO
LinkDB: A0A0D2KIC8_9EURO
Original site: A0A0D2KIC8_9EURO 
ID   A0A0D2KIC8_9EURO        Unreviewed;       262 AA.
AC   A0A0D2KIC8;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   05-JUN-2019, entry version 20.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN   ORFNames=Z520_01702 {ECO:0000313|EMBL:KIY03235.1};
OS   Fonsecaea multimorphosa CBS 102226.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae;
OC   Fonsecaea.
OX   NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIY03235.1, ECO:0000313|Proteomes:UP000053411};
RN   [1] {ECO:0000313|EMBL:KIY03235.1, ECO:0000313|Proteomes:UP000053411}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 102226 {ECO:0000313|EMBL:KIY03235.1,
RC   ECO:0000313|Proteomes:UP000053411};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; KN848063; KIY03235.1; -; Genomic_DNA.
DR   RefSeq; XP_016637357.1; XM_016772218.1.
DR   EnsemblFungi; KIY03235; KIY03235; Z520_01702.
DR   GeneID; 27707448; -.
DR   OrthoDB; 1509443at2759; -.
DR   Proteomes; UP000053411; Unassembled WGS sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR011425; Med9.
DR   Pfam; PF07544; Med9; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053411};
KW   Nucleus {ECO:0000256|RuleBase:RU364145};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053411};
KW   Transcription {ECO:0000256|RuleBase:RU364145};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145}.
FT   REGION        1     35       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
FT   REGION       54    129       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
FT   REGION      210    262       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
FT   COILED      168    195       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS      1     15       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
FT   COMPBIAS     54    109       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
FT   COMPBIAS    110    124       Pro-rich. {ECO:0000256|MobiDB-lite:
FT                                A0A0D2KIC8}.
SQ   SEQUENCE   262 AA;  28216 MW;  F0555B195869F5C1 CRC64;
     MPSSTNNTSP ANATPAAHAQ AHPDIPPFPS PSTFSILPDI WLLLARLNIL HQHPQQQQQQ
     TQAQAQTNGH HQQQQPGSSQ QGHSTSTSQN PPSTSTPSQA SQQQTQSQTQ SQPPPPPPPP
     PSGTTTTTAA TAPATFHNLP LLDLKDLPAQ IYPLKQRLAK ARAAVTSLPD VNRTVDEQED
     EIRRLERMVQ GLRGRLGRFG EIAAAAAAAT AGIEAGRDVE MKDEDENEDE EMRDEPMEHR
     QEEGGVVAQE AGGMVKNEGE EG
//
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