ID A0A0D2KR37_9EURO Unreviewed; 518 AA.
AC A0A0D2KR37;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=Z520_04754 {ECO:0000313|EMBL:KIX99178.1};
OS Fonsecaea multimorphosa CBS 102226.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Fonsecaea.
OX NCBI_TaxID=1442371 {ECO:0000313|EMBL:KIX99178.1, ECO:0000313|Proteomes:UP000053411};
RN [1] {ECO:0000313|EMBL:KIX99178.1, ECO:0000313|Proteomes:UP000053411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 102226 {ECO:0000313|EMBL:KIX99178.1,
RC ECO:0000313|Proteomes:UP000053411};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Fonsecaea multimorphosa CBS 102226.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; KN848069; KIX99178.1; -; Genomic_DNA.
DR RefSeq; XP_016633301.1; XM_016775258.1.
DR AlphaFoldDB; A0A0D2KR37; -.
DR STRING; 1442371.A0A0D2KR37; -.
DR GeneID; 27710500; -.
DR VEuPathDB; FungiDB:Z520_04754; -.
DR OrthoDB; 3280806at2759; -.
DR Proteomes; UP000053411; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09280; RNase_HI_eukaryote_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 2.
DR Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 2.
DR InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR InterPro; IPR011320; RNase_H1_N.
DR InterPro; IPR037056; RNase_H1_N_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF01693; Cauli_VI; 2.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF55658; L9 N-domain-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053411}.
FT DOMAIN 237..463
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 316..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 465..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 57112 MW; 2CFE6EFC00DADDCA CRC64;
MAQPSLPSQA NDASRSSPSL VSQNAAAGVK RKRTAERKYY AVRQGKTPGI YDTWTDCLGQ
VKGHKGAVFK AFQSLQEAQA FMDGKTLANT NSSKEQKFYA VQNGRVPGVY TDWIQAQAQI
RGISKPKHKK FNTRAEAEAF VAAGAKANGS ESAHSATPEE EIRRLIVRRS APGLQINGTY
SPTDKDGNPY EVGRGPLPPD AEDGYDPNVR LGPDGTIVNR TEEEKNRTKM MARQKESPGM
LRIYTDGSSL RNGQAGARAG VGVFFGPQDP KYANSPSSKP KSKPKSKSKL KPVRYTASNK
PQLVYTMDWT ARQLGSDDGR AKKRQAGEED DDETEKGTEK LTNWRYRNVS EALKGSKQTN
QRAELTAILR ALDIAPRHRE VTIYTDSKYA IDCVTNWYRN WKKNGWVNSK GKPVENKDLV
MDIREKIEER EHLGKVTYFV WVKGHMNNPG NIAADRLAVQ GAMTGRGLED GTDEGSKGAE
GGGENAALGE GELEVDEEAA IFRAMELAME EDLDAQFQ
//
