ID A0A0D2M9Y0_9CHLO Unreviewed; 485 AA.
AC A0A0D2M9Y0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Aquaporin NIP1-2 {ECO:0000313|EMBL:KIY97776.1};
GN ORFNames=MNEG_10184 {ECO:0000313|EMBL:KIY97776.1};
OS Monoraphidium neglectum.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Selenastraceae; Monoraphidium.
OX NCBI_TaxID=145388 {ECO:0000313|EMBL:KIY97776.1, ECO:0000313|Proteomes:UP000054498};
RN [1] {ECO:0000313|EMBL:KIY97776.1, ECO:0000313|Proteomes:UP000054498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 48.87 {ECO:0000313|EMBL:KIY97776.1,
RC ECO:0000313|Proteomes:UP000054498};
RX PubMed=24373495; DOI=10.1186/1471-2164-14-926;
RA Bogen C., Al-Dilaimi A., Albersmeier A., Wichmann J., Grundmann M.,
RA Rupp O., Lauersen K.J., Blifernez-Klassen O., Kalinowski J., Goesmann A.,
RA Mussgnug J.H., Kruse O.;
RT "Reconstruction of the lipid metabolism for the microalga Monoraphidium
RT neglectum from its genome sequence reveals characteristics suitable for
RT biofuel production.";
RL BMC Genomics 14:926-926(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|RuleBase:RU000477}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
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DR EMBL; KK102432; KIY97776.1; -; Genomic_DNA.
DR RefSeq; XP_013896796.1; XM_014041342.1.
DR AlphaFoldDB; A0A0D2M9Y0; -.
DR GeneID; 25727321; -.
DR KEGG; mng:MNEG_10184; -.
DR OrthoDB; 4064096at2759; -.
DR Proteomes; UP000054498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45624:SF15; MITOCHONDRIAL ARGININE TRANSPORTER BAC1; 1.
DR PANTHER; PTHR45624; MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED; 1.
DR Pfam; PF00230; MIP; 1.
DR Pfam; PF00153; Mito_carr; 2.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Reference proteome {ECO:0000313|Proteomes:UP000054498};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 43..126
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 180..267
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 130..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 49046 MW; 03FD853200271E72 CRC64;
MPAAAWLTHT CRRGAALLNR AWQVYSRLLA AFRDPSAPPG QPAPLHIVPF AGAGAGFALS
LILGPTELLK CRLQTTSHKA GPSEILRHVI AEEGLMGLTR GLGATFIREV PGNALFFTTY
EWLRRTEWLG SGSGGRSREA GGDNSSSSNS SSISNNSSSS CSSSSRSSNR AVEQLWAAAR
GAGSAIVCGG LAGVAMWGTI LPLDVAKSRI QVARPGGPWD VGVAAHLRML WAEGGARALW
SGLTPTLVVV HASDDDAVLT RAMLGEFTGS TIFQLIGSAA AAGGAGAAIA ANSLGLIPLI
YAFAAISGAH FNPAVSFMFL LNGTFNFKKF LSYAVAQIAG CVLGALLCTV LLPGVTVGMG
AAGPGAWAPA AGVAATAIFG WECIMTAFLC ITVNNTSPGK PGASVASPIG VGLVVMASAL
ACGALTGSLL NPARALGPAL VFQHLGAGTV ALYLSAQLAG AALASTLCQA LGGGDEPRRA
ARAAA
//
