ID A0A0D2MVW0_9CHLO Unreviewed; 441 AA.
AC A0A0D2MVW0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=3-ketoacyl-CoA synthase {ECO:0000256|PIRNR:PIRNR036417};
DE EC=2.3.1.- {ECO:0000256|PIRNR:PIRNR036417};
GN ORFNames=MNEG_1319 {ECO:0000313|EMBL:KIZ06635.1};
OS Monoraphidium neglectum.
OC Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC CS clade; Sphaeropleales; Selenastraceae; Monoraphidium.
OX NCBI_TaxID=145388 {ECO:0000313|EMBL:KIZ06635.1, ECO:0000313|Proteomes:UP000054498};
RN [1] {ECO:0000313|EMBL:KIZ06635.1, ECO:0000313|Proteomes:UP000054498}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SAG 48.87 {ECO:0000313|EMBL:KIZ06635.1,
RC ECO:0000313|Proteomes:UP000054498};
RX PubMed=24373495; DOI=10.1186/1471-2164-14-926;
RA Bogen C., Al-Dilaimi A., Albersmeier A., Wichmann J., Grundmann M.,
RA Rupp O., Lauersen K.J., Blifernez-Klassen O., Kalinowski J., Goesmann A.,
RA Mussgnug J.H., Kruse O.;
RT "Reconstruction of the lipid metabolism for the microalga Monoraphidium
RT neglectum from its genome sequence reveals characteristics suitable for
RT biofuel production.";
RL BMC Genomics 14:926-926(2013).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|PIRNR:PIRNR036417}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|PIRNR:PIRNR036417}.
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DR EMBL; KK100348; KIZ06635.1; -; Genomic_DNA.
DR RefSeq; XP_013905654.1; XM_014050200.1.
DR AlphaFoldDB; A0A0D2MVW0; -.
DR STRING; 145388.A0A0D2MVW0; -.
DR GeneID; 25730627; -.
DR KEGG; mng:MNEG_1319; -.
DR OrthoDB; 930987at2759; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000054498; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR012392; 3-ktacl-CoA_syn.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR013601; FAE1_typ3_polyketide_synth.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR31561; 3-KETOACYL-COA SYNTHASE; 1.
DR PANTHER; PTHR31561:SF23; 3-KETOACYL-COA SYNTHASE; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF08392; FAE1_CUT1_RppA; 1.
DR PIRSF; PIRSF036417; 3-ktacl-CoA_syn; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|PIRNR:PIRNR036417,
KW ECO:0000313|EMBL:KIZ06635.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054498};
KW Transferase {ECO:0000256|PIRNR:PIRNR036417, ECO:0000313|EMBL:KIZ06635.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 31..315
FT /note="FAE"
FT /evidence="ECO:0000259|Pfam:PF08392"
FT DOMAIN 333..409
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
SQ SEQUENCE 441 AA; 48824 MW; 97E7242F0452B0BA CRC64;
MASAPALAVR LWVCGAALLL SAALLWRTFS RRRTYLVDYS VYRSPDSWKV SKKEYDAIVA
STNNFSPESL QFMSKVLARS GLGDETYAPP SLTNVPMSLN MAACRFEFES VAFGAVKDLL
NKVNVSPKQI GVVITNSSLF NTTPSLSATI MNHFGMGSNT INYNLGGMGC SAGVIAADLA
RQMLEIYPNT YALVVSTENL TYNWYPGTNR GMLVTNTIFR VGGAALLLSN KRQDSWRSKY
ELQHVVRTNL AANDAAFNCV FEVEDEAGVR GIRLGKELMG VAGQALKKNI TTLGPKVLPL
SEQLLFAANM LARKVYGSKR VKAYVPNFKK AFNHICIHTG GRAVIDEIEK QLTLGRETVE
PSRASLFRFG NVSSSSIWYC LAYIESYRGL KRGDTVWQLG FGSGFKCNSA VWRANRRIRD
SHSAWEGFDV EHMYEQLAKM P
//
