ID A0A0D2NWQ0_GOSRA Unreviewed; 602 AA.
AC A0A0D2NWQ0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=9-cis-epoxycarotenoid dioxygenase NCED6, chloroplastic {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_006G219900 {ECO:0000313|EMBL:KJB37787.1}, Gorai_001563
GN {ECO:0000313|EMBL:MBA0588461.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB37787.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB37787.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
RN [2] {ECO:0000313|EMBL:MBA0588461.1, ECO:0000313|Proteomes:UP000593578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8 {ECO:0000313|EMBL:MBA0588461.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:MBA0588461.1};
RX PubMed=30476109;
RA Grover C.E., Arick M.A. 2nd, Thrash A., Conover J.L., Sanders W.S.,
RA Peterson D.G., Frelichowski J.E., Scheffler J.A., Scheffler B.E.,
RA Wendel J.F.;
RT "Insights into the Evolution of the New World Diploid Cottons (Gossypium,
RT Subgenus Houzingenia) Based on Genome Sequencing.";
RL Genome Biol. Evol. 11:53-71(2019).
RN [3] {ECO:0000313|EMBL:MBA0588461.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=8 {ECO:0000313|EMBL:MBA0588461.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:MBA0588461.1};
RA Grover C.E., Arick M.A. II, Thrash A., Conover J.L., Sanders W.S.,
RA Peterson D.G., Scheffler J.A., Scheffler B.E., Wendel J.F.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001745; KJB37787.1; -; Genomic_DNA.
DR EMBL; JABEZZ010000006; MBA0588461.1; -; Genomic_DNA.
DR RefSeq; XP_012486873.1; XM_012631419.1.
DR AlphaFoldDB; A0A0D2NWQ0; -.
DR STRING; 29730.A0A0D2NWQ0; -.
DR EnsemblPlants; KJB37787; KJB37787; B456_006G219900.
DR GeneID; 105800347; -.
DR Gramene; KJB37787; KJB37787; B456_006G219900.
DR KEGG; gra:105800347; -.
DR eggNOG; KOG1285; Eukaryota.
DR OMA; NPYTHHP; -.
DR OrthoDB; 318119at2759; -.
DR Proteomes; UP000032304; Chromosome 6.
DR Proteomes; UP000593578; Unassembled WGS sequence.
DR GO; GO:0009570; C:chloroplast stroma; IEA:EnsemblPlants.
DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:EnsemblPlants.
DR GO; GO:0045549; F:9-cis-epoxycarotenoid dioxygenase activity; IEA:EnsemblPlants.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010114; P:response to red light; IEA:EnsemblPlants.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543:SF101; 9-CIS-EPOXYCAROTENOID DIOXYGENASE NCED6, CHLOROPLASTIC; 1.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00022964};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT REGION 38..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..56
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 295
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 344
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 409
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 588
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 602 AA; 67422 MW; 1B36FDEDF5766E6F CRC64;
MQPSLHFFTP KHQSLPQTQS PLFTCKFIVN PAKKTVPRNP LPLLSPPAPS RSPPHPEVVE
PMVQRERSNV LVPQHPNYPV HLNRFQKLAA VALDKIETSV IMRLEKNHVL PKMVDPEVQI
SGNFAPVEEC PVHHGLEVVG RIPACLRGVY VRNGANPMFA PSGGHHLFDG DGMIHAISLG
LGNKASYSCR YTRTSRLVQE ARFGRCMFPK PIGELHGHLG LARLGLYMAR AGLGLVDGSH
GTGVANAGLV YFNGRLLAMS EDDLPYHVKI TGEGDLETIG RFNFSDQIDC PLIAHPKLDP
VTGDLHTLNY NVLKKPYLKY FRFDKFGRKS GDLHVDIDQA TMIHDFAITE NFVVIPDHQM
VFKLSEMIRG GSPVVYNKNK TSRFGVLQQN DVVGSGIQWI NVPNCFCFHL WNAWEEISDA
GDKIIVVIGS CMNPPDSIFN ESKDTFRSEL SEIRMNLRTR QSTQRVIVSG MNLEAGQVNG
QYLGQKTRFV YLAIADPWPK CSGMAKVDLQ TGKVTKFMYG TWRYGGEPFF VPDKKQTCNR
NGNEDEGYIM GLVRDEKKEM SEMVIVKGSN MEQVAAIRLP SRVPYGFHGT FISQEELRRQ
VI
//
