ID A0A0D2P332_GOSRA Unreviewed; 1243 AA.
AC A0A0D2P332;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=B456_003G173800 {ECO:0000313|EMBL:KJB20948.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB20948.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB20948.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001742; KJB20948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2P332; -.
DR EnsemblPlants; KJB20948; KJB20948; B456_003G173800.
DR Gramene; KJB20948; KJB20948; B456_003G173800.
DR eggNOG; ENOG502QVBR; Eukaryota.
DR OMA; HIANRCE; -.
DR Proteomes; UP000032304; Chromosome 3.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF305; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 9..176
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1243 AA; 142012 MW; CB919C7B971C2CA7 CRC64;
MAMSEISRCS YHVFLSFRGE DTRKSFTDHL YTALVHLGIQ TFRDDEEIER GNNIKDEIEK
AILHHSKISI VVFSKNYAAS TWCLNELVMI LEHKKSSKHS VLPVFYDVDP SQVKNQTGSY
AEAFTQHEQN FESETNMVQR WRNALKEVAD IGGMVLQDRH ESQFIQDIVK EVQNKLHLIS
LYVPPYLVGI DSLVTQINQW LEQDGANKVG IATICGIGGI GKTTIAKVVY NQNIPRFEGY
SFLADVRETS PDCNGLVRLQ RRVLLVLDDV DELEKIRKLM GTQIPFHLGS KIIITSRNRC
LLNAHFISQM FELEASTSCG GLSKLFEVKE LASSESLQLF NWYAFGHNSV PESLMAYARS
LVKHCGGLPL ALQVLGSSLS SKSVSSWKSA LEKLEEIPDS KIQEILRISY DSLEDDHDKN
LFLDIVCLFI GKDRDYTTTI LDGCDFYTTI GIENLVGRSL LIINEKNKLM MHQMIRDMGR
EIIRQESSNI GKRSRLWHKN AFDVIREKIG SRTVKCLTLD LKRLLEDKAK RTNTTLHFPK
HSKSQFLMAN DVDMETQAFA KMKRLKLLQL DYCLPNLKIL NLNHSHSLLK TPSFSGLPSL
EKLMLKYCIN LVEIDQSIGE LKMLTFLNLK DCTSLRKLPR TIGSLISLEE LILSGCSRLD
DVPRELHNME SLKVLNLDET AIYQSRLGLH WLLLKRSKGL GFSWASLPDS LVKLSLESCK
LSNDVMPNDL CNLASLKSLN LSRNPIHYLP ESLKNLTKLE ELLLTSCTEL QMIPKLPVLL
NVFECKFIFG DNSSFHGYTV IIPCFFSSTR CIIFGCEKLT EVEDLFKLEP IENFEAEEIR
RLFKVDSINR NRLQLYSYLT DSIMLATPQV LQECGITSTF VVGSEVPIGF KHGTTEHRIS
FFLPTPSHPD EKIHRFSLCI VFSLASDQML ELIPSVHIFN ETKRIMQRYR SSFIGIPETN
DNTMLWLIHW PVTDCQFEAG DLVSCAVVPI HLSIRKFGVT YESEHNIRYE YGFSHLSTGD
EVSTRNIKMD LTRHLPSLES YGNVKVQLCS YIEESKVIAS PQVLYDYSII TTFDPLPFDY
HGHYCGHQAG KTEVSISVPP NSSRKISCFL NSIIIFSAKN DKTYGFLPCL EIVNETKGTK
WTYSKHFMGI PETKNTLYWT TCWNFRSDEL EAGDHISLRV LSDLSVLEFG INLVYDYELE
DNPNFFSQLP WMSKCFKYLL GIFVYVSSKS QKDLYRLQSL DKC
//
