ID A0A0D2P6W8_GOSRA Unreviewed; 335 AA.
AC A0A0D2P6W8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CMP-sialic acid transporter 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_007G106100 {ECO:0000313|EMBL:KJB41472.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB41472.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB41472.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. CMP-
CC Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
CC {ECO:0000256|ARBA:ARBA00006447}.
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DR EMBL; CM001746; KJB41472.1; -; Genomic_DNA.
DR EMBL; CM001746; KJB41474.1; -; Genomic_DNA.
DR RefSeq; XP_012490070.1; XM_012634616.1.
DR RefSeq; XP_012490071.1; XM_012634617.1.
DR RefSeq; XP_012490072.1; XM_012634618.1.
DR AlphaFoldDB; A0A0D2P6W8; -.
DR EnsemblPlants; KJB41472; KJB41472; B456_007G106100.
DR EnsemblPlants; KJB41474; KJB41474; B456_007G106100.
DR Gramene; KJB41472; KJB41472; B456_007G106100.
DR Gramene; KJB41474; KJB41474; B456_007G106100.
DR eggNOG; KOG2234; Eukaryota.
DR OMA; FGMMAYD; -.
DR OrthoDB; 200085at2759; -.
DR Proteomes; UP000032304; Chromosome 7.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015711; P:organic anion transport; IEA:UniProt.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR NCBIfam; TIGR00803; nst; 1.
DR PANTHER; PTHR10231; NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR10231:SF43; UDP-GALACTOSE TRANSLOCATOR; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..335
FT /note="CMP-sialic acid transporter 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007395408"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 335 AA; 37781 MW; AA1FA460057F4441 CRC64;
MKWYIAAFLL TVLTSSQGIL TTLSQSNGKY KYDYATVPFL AEVFKLIISS VFLWRECKKL
PPPKMTTDWK TVRLFPIPSV IYLIHNNVQF ATLMYLDTST YQIMGNLKIV TTGILFRLFL
KKKLSNLQWM AIILLAVGTT MSQVQGCGEA SCDSLFSAPI QGYMLGVLSA CLSALAGVYT
EFLMKQNNDS LYWQNVQLYT FGAILNMARL VVDDFRAGYE KGPWWQRLFN GYSVTTWMVV
LNLGSTGLLV SWLMKYADNI VKVYSTSMAM LLTMVLSVFL FSFKPTLQLF LGIIICMMSL
HMYFAPPSML VGLPPTVRSD PDSLVIVSDD HKAES
//
