ID A0A0D2PMI0_GOSRA Unreviewed; 536 AA.
AC A0A0D2PMI0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Xanthine/uracil/vitamin C permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_001G061700 {ECO:0000313|EMBL:KJB08069.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB08069.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB08069.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; CM001740; KJB08069.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2PMI0; -.
DR STRING; 29730.A0A0D2PMI0; -.
DR EnsemblPlants; KJB08069; KJB08069; B456_001G061700.
DR Gramene; KJB08069; KJB08069; B456_001G061700.
DR eggNOG; ENOG502QQ5E; Eukaryota.
DR OMA; SMTMILV; -.
DR Proteomes; UP000032304; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF13; ADENINE_GUANINE PERMEASE AZG2; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 112..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 536 AA; 57502 MW; A1E7F299B01F8B5D CRC64;
MGFGASLKKL SNSWKKIEMS VNDAISKSKV GKFFKLEARK TCFTREIRAG TATFLTMVYI
ITVNATIIAD SGGTCLMADC TVPANQTAAS PDCMLKPNLG YDNCVSKTKS DLVVATILSA
MIGSFAMGVL ANLPLGLAPG MGPNAYLAYN LVGFHGSGSI SYQTALAMVL IEGCAFLAIS
TLGVRAKIAR LMPKPVRLAC GAGIGLFIAF VGLQIHQGVG LIGPDPTTLV TISACAKIDP
ISNTCVGGKM RSPTFWLAMV GFLMTCYGLM KEIKGSMIYG ISFITLVSWI RGTSFTIFPK
TPLGDTNYNY FKKVVDFHKI ESTFGVISFS HFNRPEVWIA LVTLLYVDVL ATTGTLYTMA
EIGGFLDDKG SFEGEYLAYI VDASSTIVGS ALGVSPVATY VESSAGIKEG GRTGLTAVVI
AFYFFLSLFF TPLLTSVPPW AIGPSLVIVG VMMMKVVKDI NWENIKEAVP AFVTMSIMPL
TYSIANGIIG GIGVYIALSL YDLMLGFIKW VNKMRKMVIK EQNQVSNGVE SMVEII
//
