ID A0A0D2QW42_GOSRA Unreviewed; 546 AA.
AC A0A0D2QW42;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=B456_001G259300 {ECO:0000313|EMBL:KJB11435.1}, Gorai_021906
GN {ECO:0000313|EMBL:MBA0579657.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB11435.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB11435.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
RN [2] {ECO:0000313|EMBL:MBA0579657.1, ECO:0000313|Proteomes:UP000593578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8 {ECO:0000313|EMBL:MBA0579657.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:MBA0579657.1};
RX PubMed=30476109;
RA Grover C.E., Arick M.A. 2nd, Thrash A., Conover J.L., Sanders W.S.,
RA Peterson D.G., Frelichowski J.E., Scheffler J.A., Scheffler B.E.,
RA Wendel J.F.;
RT "Insights into the Evolution of the New World Diploid Cottons (Gossypium,
RT Subgenus Houzingenia) Based on Genome Sequencing.";
RL Genome Biol. Evol. 11:53-71(2019).
RN [3] {ECO:0000313|EMBL:MBA0579657.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=8 {ECO:0000313|EMBL:MBA0579657.1};
RC TISSUE=Leaf {ECO:0000313|EMBL:MBA0579657.1};
RA Grover C.E., Arick M.A. II, Thrash A., Conover J.L., Sanders W.S.,
RA Peterson D.G., Scheffler J.A., Scheffler B.E., Wendel J.F.;
RL Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM001740; KJB11435.1; -; Genomic_DNA.
DR EMBL; JABEZZ010000001; MBA0579657.1; -; Genomic_DNA.
DR RefSeq; XP_012443823.1; XM_012588369.1.
DR AlphaFoldDB; A0A0D2QW42; -.
DR EnsemblPlants; KJB11435; KJB11435; B456_001G259300.
DR GeneID; 105768447; -.
DR Gramene; KJB11435; KJB11435; B456_001G259300.
DR KEGG; gra:105768447; -.
DR eggNOG; ENOG502QPJU; Eukaryota.
DR OMA; QLCTPRI; -.
DR OrthoDB; 1212342at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000032304; Chromosome 1.
DR Proteomes; UP000593578; Unassembled WGS sequence.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:EnsemblPlants.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23315:SF339; U-BOX DOMAIN-CONTAINING PROTEIN 40; 1.
DR Pfam; PF00514; Arm; 2.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 64..138
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 311..348
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 546 AA; 59953 MW; 7EEC6185DA28F7D8 CRC64;
MEFQEALMKL VIHKTPTHHH KDFFHSISGK DEKVVSKKQK WKISFHRSSS AKTSQSGHQV
QSKSIPEEFF CPISGSLMAD PVIVSSGHTF ERVCVEACKN LDFAPILKDG SVPDFSTVIP
NLALKSTIVN WCQTHLINPP KPFDFSKAEE LVRSLSSKKP KTQIEKDVPS VKLDHAVTEL
IRSSSEESVS AVTTTPTQPL QLADSPSCYS SASSSSEIET LTTPNINEEE EYFLTKLKSH
QVFDIEEALI TLRKKTRTQE SSRVVLCTPR VLSAFRSLIV SRYVNIQVNS VAVLVNLSLE
KTNKVKIVRS GLVPDLIDVL KSGSPEAQEH ACGALFSLAL DDHNKTAIGV LGALQPLMHM
LRSGSERTRH DSALALYHLS LVQSNRTKLV KIGSVPVLLS MVKSGHMTGR VFLILCNLAS
GSDGRAAMLD SGAVDCLVKL LKGSELDEPT REGCVAVLYG LSQAGLRFKG LAKAAGAVEE
LAKVERTTNG LTREKARKMW ETLKRGSEEE QEEVDWEALL DSGFMTRTKF RFGGGKDGSC
VNSSEF
//
