ID A0A0D2RTE3_GOSRA Unreviewed; 1718 AA.
AC A0A0D2RTE3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0000259|Pfam:PF00931};
GN ORFNames=B456_011G265100 {ECO:0000313|EMBL:KJB73982.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB73982.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB73982.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM001750; KJB73982.1; -; Genomic_DNA.
DR EnsemblPlants; KJB73982; KJB73982; B456_011G265100.
DR Gramene; KJB73982; KJB73982; B456_011G265100.
DR eggNOG; KOG4658; Eukaryota.
DR OMA; KRCAVDN; -.
DR Proteomes; UP000032304; Chromosome 11.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR33463; NB-ARC DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR33463:SF205; RPP4C3; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 165..396
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 30..64
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1718 AA; 195569 MW; 3B480F0078BEE7EE CRC64;
MEFVTTLVGS IVTKAVEYTI SPIKNHVKYL SNHQQYVETL KDRAERLKDA RDRVQHSVDA
AKRNGEETEA DAGKWLSAAD KKILEQVEKV MQDEEKAKKK CFIGLCPNFR TRYKLSLKAE
EEAKAVAELL EHGKFERVSY RAVPQGIVVA PVKGYEEFES RTSILNGIME ALKDDSVSVV
GVHGMGGIGK TTLVKEIARK VKGRLFDSVV IATVTQAIDI EKIQNQIADF LGLKFEEQSM
VGKAFRLRER LKKEERILVV LDDIWGKVDI EEVGIPLGDE HKGCKLLLTS RELNVLSNGM
DAQKNFPIGF LNEKEAWELF KKKAGDCDES CDLKPIATEV AKKCAGLPIA IETVAGALRN
KRLFEWKNAL RELERPSSSN FTGIAAAYSA IEWSFNYLES EEIKLTFLLC SVIGHNGLVE
DLVRYTLGLG LFDGVHTMEE ARNKVLTVVA NLKASALLLD SYNDKLFDIH DVVWDAAIAI
ALKDYRMLVL RDHAPKEWSD KEKMKTWSVI SLRCPQIIAN LPKEMECSGL SFCHMAYDGA
VKIPLNFFKQ TEGLKALDLV GMQFPSLPES IIHLADLRML CLKRCAVDNI TILGELKNLE
ILDLAASGIK ELPKEMAQLT QLRLLDLRGC RELKIIPPNV LSGLSKLEEL YMSRSFVEWE
KGGVVENERK NASLDELNNL PCLTTLYVHI LDVQMIPKHR FVETLDRFRI FVGNYGMYDC
CNNYESPKAL KLMLYTNIDL DNGMKKLLIK TEDLCLEGLE GVKNVLVELN NGKDLPNLKR
LHVKNGRHVQ YIKTNKIGFS ELCFITLENL PQLVSFCSPD ERCSTKPLLL LNKQTCHWIT
NLRSLIIKGC GKLEHLLSPS LARSLVQLQC FEIEDCNCLR DIILTEEIEE ERKDVICFPR
LNSLRIDRLP NLIFFSSGNH NIEFPLLKKL EIKRCPKLID SSVAVPSLED MTIWDLSNVK
MIFYNDLPPG SFKNLRKINV WGCGSLKNLF PASIAKDLPQ LEHLSITDCG VEEIVSKGDG
VEEQPVIPKL EELELRIFGD MDQFPPDLFQ HVKVFAVRGA SRFFSFPPLR RFYNLERLEV
SHFDFKHVVP CKGGAGTLPP IRNLKLDSAR NLKHIWRKGS ELDHILSNLQ TLTVHNCDNW
INIRVFSSSL QNLRILNVSL CKMMTNLVTP SVLKNLVQLT TMIVRGCTKM TEIVGNEGDC
HQTIVVSELK CLQLCNMKSL TSFCPRNYNF EFPCLEELVV ERCPRLKIFS EGVLSTPQLQ
RIKQSRFSNK WSWRSDLNTT IQQLYTEKVQ NILDFKILSS LQFYKCSSLK YIFTPSMLLS
LNQLHWLEVK ECSSMEQVVR EEEEAMTHKF TFLSLLSVTI ESCSNLTNFH LGSQALEFPM
LTKDLVQLRR LRILDCNMME QVIFTDGLVE NYFEFHCLAY LTLRNCPLLK TFISKCVPGD
EPQIGQHEQA SNLEVQNSSL LNEKDTFPVL EELTLKTNDL VKGICDEQLS LQCFQNLKLL
NLHCFRKRST TLPYWFIRSL PKLQKLVIKN ASISEIVRSE GLSDEERHTS AFYQLKELSL
TQLPGLTLKT FEPSLLSFKN LTTLEVSRCH GFINLIACST AKCLTLLERL SIDDCEMIEE
IIACEAEEIQ GGIVFPKLKY LQLSCLPCLA SFSLAHHSLE FPVLLMVMVT KCPQMRNFCQ
GDLSTPRLEQ MHLTRDEEGE LQNHLKDLNS CVFTYIHS
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