ID A0A0D2SRF7_GOSRA Unreviewed; 1121 AA.
AC A0A0D2SRF7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=B456_007G260800 {ECO:0000313|EMBL:KJB44606.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB44606.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB44606.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM001746; KJB44606.1; -; Genomic_DNA.
DR RefSeq; XP_012492550.1; XM_012637096.1.
DR AlphaFoldDB; A0A0D2SRF7; -.
DR STRING; 29730.A0A0D2SRF7; -.
DR EnsemblPlants; KJB44606; KJB44606; B456_007G260800.
DR GeneID; 105804455; -.
DR Gramene; KJB44606; KJB44606; B456_007G260800.
DR KEGG; gra:105804455; -.
DR eggNOG; KOG2171; Eukaryota.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000032304; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR007701; Interferon-rel_develop_reg_N.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527:SF102; BETA-3, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF05004; IFRD; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 42..116
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 424..462
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1121 AA; 124030 MW; A4CB3976EF09F590 CRC64;
MATDQTQLQL AQLAHILGPD STHFETLISH LMSSSNDQRS QAESLFHLAK QTHPDSLSLA
LSRVLSSSPR PELRALSAVL LRKILTPAAD YSFLFPLLAE STRAAIKASL LSSLQTEQSK
ANVKKLCDTI SELASSVVAT RGWPELLPFL FQCVNSKNPN LEESALLIFS RLAQNVGETT
ETLIPHLNTL HSVFFNCLSN PSSCDVRIAA LSASVSFIQC ISNPKDRDAF QDLLPLMMQT
LTEALNSGLE ATAQEALELL IELAGTEPRF LRRQIMEVVG SMLQIAEAES LEEGTRHLAI
EFIITLAEAR ERAPGMMRKL PQFIRRLFWV LMNLLVDIED EPDWYNAESE DEDAGETSNY
GVGQECLDRL SISLGGNTVV PVASELFPVF LAASEWQKRH AALIALAQIA EGCSKVMIRN
LEQVVSMVLN SFHDAHPRVR WAAINAIGQL STDLGPELQT QYHQRVLPAL AGAMDDFQNP
RVQAHAASAV LNFSENCTPD ILTPYLDGIV SKLLVLLQNG KQMVQEGALT ALASVADSSQ
EQFQKYYDAV MPYLKAILVN ANDKSNRMLR AKAMECISLV GMAVGKEKFR DDAKQVMDVL
MSLQVSQMES DDPTTSYMLQ AWARLCKCLG QDFLPYMSVV MPPLLQSAQL KPDVTITSAD
SDANADDDDD ESIETITLGD KRIGIKTSVL EEKATACNML CCYADELKEG FFPWIDQVAT
TLVPLLKFYF HEEVRKAAVS AMPELLRSAK LAVEKGQAQG RNGTYIKQLT DYIIPALVEA
LHKEPEVEIC GSMLDSLNEC IEICGPFLDE GQIKCIVDEI KQVITASSAR KQERAERAKA
EDFDEEEGEM LKEENEQEEE VFGQLGDLLG TLIKTFKASF LPFFQELTSY ITPMWGKDKT
AEERRVAICI FDDIAEHCRE AALKYYDTYL PFLLEACNDE SPDVRQAAAF GVGLCAEFGG
SVFKPLIQEA LSRLNAVIRH PNALHLDNVM AYDNAVSALG KICQFHRDSI DAAQILPAWL
SCLPIKGDLI EAKIVHEQLC SMVERSDQEL LGPNNQYLPK IVSVFAEVLC AGKDLATEQT
ASRMINLIRH FQQSLPASTL ASTWSSLQPQ QQLALQSILS S
//
