ID A0A0D2SZI6_GOSRA Unreviewed; 410 AA.
AC A0A0D2SZI6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=THIF-type NAD/FAD binding fold domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_008G030900 {ECO:0000313|EMBL:KJB47536.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB47536.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB47536.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- PATHWAY: Protein modification; protein sumoylation.
CC {ECO:0000256|ARBA:ARBA00004718}.
CC -!- SIMILARITY: Belongs to the ubiquitin-activating E1 family.
CC {ECO:0000256|ARBA:ARBA00005673}.
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DR EMBL; CM001747; KJB47536.1; -; Genomic_DNA.
DR EMBL; CM001747; KJB47540.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2SZI6; -.
DR EnsemblPlants; KJB47536; KJB47536; B456_008G030900.
DR EnsemblPlants; KJB47540; KJB47540; B456_008G030900.
DR Gramene; KJB47536; KJB47536; B456_008G030900.
DR Gramene; KJB47540; KJB47540; B456_008G030900.
DR UniPathway; UPA00886; -.
DR Proteomes; UP000032304; Chromosome 8.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR GO; GO:0016925; P:protein sumoylation; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.10.520; Ubiquitin activating enzymes (Uba3). Chain: B, domain 2; 1.
DR Gene3D; 3.50.50.80; Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1; 1.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR042449; Ub-E1_IAD_1.
DR InterPro; IPR023318; Ub_act_enz_dom_a_sf.
DR InterPro; IPR019572; UBA_E1_SCCH.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF5; SUMO-ACTIVATING ENZYME SUBUNIT 2; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00899; ThiF; 1.
DR Pfam; PF10585; UBA_E1_SCCH; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 4..400
FT /note="THIF-type NAD/FAD binding fold"
FT /evidence="ECO:0000259|Pfam:PF00899"
FT DOMAIN 314..366
FT /note="Ubiquitin-activating enzyme SCCH"
FT /evidence="ECO:0000259|Pfam:PF10585"
SQ SEQUENCE 410 AA; 45607 MW; 211C9B58D6FDDC3B CRC64;
MASEEQISAI KGAKVLMVGA GGIGCELLKT LALSGFQDIH IIDMDTIEVS NLNRQFLFRQ
SHVGQSKAKV ARDAVLRFRP NISITPYHAN VKESRFNVDF YKEFDVVLNG LDNLDARRHV
NRLCLAADVP LVESGTTGFL GQVTVHLKGK TECYECQAKP APKTYPVCTI TSTPSKFVHC
IVWAKDLLFA KLFGDKNLEN DLNVRSSDAT NLSEHSEDVF ECRKGEDIEQ YGRRIYDHVF
GHNIEVALSN EETWKNRNKP CAIYSKDVFP DKLTKENGKT EKGSTTEDVS AMASLGLKNP
QDVWSLAENS RVFYESLRLF FSKRQKEIGN LTFDKDDQLA VEFVTAAANI RASSFGIPLH
SLFEAKGIAG NIVHAVATTN AIIAGLIVIE AIKVLKKDSN NYRFSSVILH
//
