ID A0A0D2TEP9_GOSRA Unreviewed; 1044 AA.
AC A0A0D2TEP9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=B456_011G280700 {ECO:0000313|EMBL:KJB74228.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB74228.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB74228.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
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DR EMBL; CM001750; KJB74228.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2TEP9; -.
DR STRING; 29730.A0A0D2TEP9; -.
DR EnsemblPlants; KJB74228; KJB74228; B456_011G280700.
DR Gramene; KJB74228; KJB74228; B456_011G280700.
DR OMA; GANHIHE; -.
DR Proteomes; UP000032304; Chromosome 11.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 11..181
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1044 AA; 119278 MW; 9782AB0B463A2646 CRC64;
MASSSSSSRQ MKHQVFLSFR GEDTRLNFTV HLLQALKDKG LNVFFDEEKL EKGEELSHAL
SQAIAASDLS ILVLSKDYAS SQSCLAELSD IMDRKRKPTD KHIVLPIFYH VDPSDVRNIG
GTFKTSFEEH ESKRPIEDMK RWKVAFAEIG ASKGWHIEGG KSDRFETEYI KDVVEYVLKK
LNSNCRSVSE ELVGIDDQKK KLLVLIEQAG IHVIGLWGMS GIGKTTLADA VYKEVSPKFE
CSLFLQNISE KIKKQGSESL RNELLSKLLN NTLSIGYPYH ERLNNKKILL VFDDVTDPDQ
MDFVGVKYFG PGSKIIVTSR DIQVLRNGGA NHIHEVKKLN MNDSFQLFST YAFQLLNLPV
DFKYLSFKFV EYAQGNPLAL KVLGLKLYTK SIKEWKSEVT KLKQCGEIKL SHILKSSLDG
LDEIEKNIFL DVACIFKGQH LNYVEKILSN YYKGARCGIS KLVGKCLLEV KYESISMHGM
LEEMGKDIVM QESEYPGKRS RLWNCKDVEE VISYDKGTDL IKGIKVDMTE VDSLQFCATA
FEKMHKLRYI NISFPKKMLW LKKLYANQVE SISLPDELRF LRWDVYPFKS LSGFNPKNLV
VLKLLHGNME QLWNEDDDMN LTNLREIDVS YCKNLRKMHN LSSAINLELL RCIGCESLVE
LWNEDDHIWW MLRSRTIIFS VHDLVHLRKI YFDGLRLNGC YSLKKFPKVP RPFCSLDSSE
TKIEEVSDSI KDHHKLETLW LGKSKVKKVS INILKLEFLR KLDLSGCPIE EVGCPKVELL
SDLPPYLEVL SVNDCTSLEK FDSLDDELCI NHNFLTRFRN CFNLNQDSTS NIEANAMLKI
GSLAKKWAAR YDWQYNPDRA PSLICCFPGN KISANMFKCQ SMKSSLCLKI APNGGSGSRF
LVFAICLVAD LTNCLEFQLR ECICEYQLTT AGGGNGGGGC ENFISEICFR SFCEPVKYMD
YHVFILSSIA MVIEDKNYEE ASFKFYIKNF HFDEDNDGGE KYIKVERCGV HVFYVDATEK
RVAGNKRSFS HDGEEGDGGL KRLK
//
