ID A0A0D2TN30_GOSRA Unreviewed; 651 AA.
AC A0A0D2TN30;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 13-SEP-2023, entry version 27.
DE RecName: Full=Macro domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_012G116900 {ECO:0000313|EMBL:KJB77018.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB77018.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB77018.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00464}.
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DR EMBL; CM001751; KJB77018.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2TN30; -.
DR EnsemblPlants; KJB77018; KJB77018; B456_012G116900.
DR Gramene; KJB77018; KJB77018; B456_012G116900.
DR Proteomes; UP000032304; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0047627; F:adenylylsulfatase activity; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:UniProt.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR019808; Histidine_triad_CS.
DR InterPro; IPR011146; HIT-like.
DR InterPro; IPR036265; HIT-like_sf.
DR InterPro; IPR002589; Macro_dom.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032566; Znf-C2HE.
DR PANTHER; PTHR12486:SF4; APRATAXIN; 1.
DR PANTHER; PTHR12486; APRATAXIN-RELATED; 1.
DR Pfam; PF11969; DcpS_C; 1.
DR Pfam; PF01661; Macro; 1.
DR Pfam; PF16278; zf-C2HE; 1.
DR SUPFAM; SSF54197; HIT-like; 1.
DR SUPFAM; SSF52949; Macro domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00892; HIT_1; 1.
DR PROSITE; PS51084; HIT_2; 1.
DR PROSITE; PS51154; MACRO; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 281..495
FT /note="Macro"
FT /evidence="ECO:0000259|PROSITE:PS51154"
FT DOMAIN 459..567
FT /note="HIT"
FT /evidence="ECO:0000259|PROSITE:PS51084"
FT REGION 174..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 71718 MW; 33D270BA2AF0063D CRC64;
MLKKRSIYLR LQDTINNGKS GTKPQCLKSA AASLKEGKSV FIDRCNLDKE QRVDFVNLGG
PEVEVHAVVL DLPAKLSISR IVKRTGHEGN LQGGKAAAVV NRMLQNKELP KLSEGFSRIT
FCRNETDVDA AVKTYTAVGP LDTLPHGCFG QKDPNAKTQL GIMRFLKRLH ETNARDSVPS
QLTEEKGPCG KTQETVSSSS GMASQKIKVS EDMAPGSISH DESDIPTLAF PSISTVDFQF
DLEKASDVIV GKVEEFMDKL GNARLVLVDL TERSKILSLV RAKAAEKKID SKRFFTFIGD
ICQLYTKGGL CCNVIANAAN WRLKPGGGGV NAAIFNAGGP ALEAATKEQA RSLLPGNALV
VPLPSTSPLY SKEGVTHVIH VLGPNMNPRR PNCLDNDYVK GCKVLEDAYS SLFKGFLSIA
NTQVKVPRSS GSILSGPSKL EDEISGTKTK TWAPCLQALY NIAMQPEKHN KQVLEASDDV
VVLNDIYPKA KQHLLVLARI KGLDTLADAR KEHLPLLMTM HEVGLRWVDK FVGEDASLVF
RLGYHSVPSM RQLHLHVISQ DFDSKNLKHK KHWNSFTTAF FRDSVDVMEE INNQGKATIQ
DEKRLMSMEL RCHRCRSAHP NIPRLKSHIS SCQAPFPADL QKKGRLVPEQ N
//
