ID A0A0D2TU70_GOSRA Unreviewed; 1010 AA.
AC A0A0D2TU70;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_009G230500 {ECO:0000313|EMBL:KJB58901.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB58901.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB58901.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
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DR EMBL; CM001748; KJB58901.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2TU70; -.
DR STRING; 29730.A0A0D2TU70; -.
DR EnsemblPlants; KJB58901; KJB58901; B456_009G230500.
DR Gramene; KJB58901; KJB58901; B456_009G230500.
DR eggNOG; KOG4271; Eukaryota.
DR Proteomes; UP000032304; Chromosome 9.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00821; PH; 1.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR025757; MIP1_Leuzipper.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR46265; RHO GTPASE-ACTIVATING PROTEIN 7; 1.
DR PANTHER; PTHR46265:SF22; RHO GTPASE-ACTIVATING PROTEIN REN1-LIKE ISOFORM X1; 1.
DR Pfam; PF14389; Lzipper-MIP1; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032304}.
FT DOMAIN 99..206
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 253..452
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..1010
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..509
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 531..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..606
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 618..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..777
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..821
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..850
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 858..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..906
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..929
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 945..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1010 AA; 111102 MW; D36C7DFDCA069631 CRC64;
MATKKDESTL LQQKMASKKE DPSKAQKMAS KKEEPSQAHQ KMEEPSQAQQ RMMPKRDERE
PSQGNQGDAS TAAAPPGPAS PTDNLNSRSG NSANSSSPIV LKSGPLFLSS KGIGWTSWKK
RWFILTHTSL VFFRSDPNAV SQKGNEVNLT LGGIDLNNSG SVVVKADKKL ITVLFQDGRD
GRTFTLKAET LDDLYEWKAA LEKALSQAPS SALSAGQNGI FGNDQAEAVD GSKEPVNDKQ
PVRSSVLHRP ILLALEDVDG APTFLEKALR FVEEHGVKVE GILRQAADVE DVERRIREYE
QGKIEFSPDE DAHVIADCVK YVIRELPSSP VPASCCNALL EACRTEHSAR VNAMRMAVLD
TFPEPNRRLL QRILNMMQIV ASHKNENRMS SSAVAACMAP LLLRPLLSGD CEIESDFDVG
GDGSMQLLQA AAAANHAQAI CITLLEEYDK IFGEGCVSHD MYSDSEESGS GSEEEADDDE
SDEDDEDYED DECDDESQES DEDDDYAESG TGSEGGHSVK SDDKDYDSSS SSSESSKSGN
YVQATKKKSS PLHPNDGSKR KEDNRISKSS ETETNKPAEL SKGVHGVTKL EDTSTRQNSI
TSASKPPAVG NGPGLNVRQG TMWRSSGSKK LSMDSIDYPI EEEAAVESLE AEKLDLQKRL
TEEIESNTIL EANLEKRKKA LHEQRLALEK EVARLEEELQ RAREKRTALE AGLNPSQGPT
SLPEKIDEKT KEDLKDIARS EADVRNLNKR VNELGTQLNQ QPEQKSVSMS DSCTQREPNH
QTKMKDKTKG AEAPMRSRSK KEMKVDKAEG EKGKKQESSM ANRHRNPVQQ EMDVDKAESE
KGKKQESSTA NKHKNPVQQE TNVDKAESEK GKKQESFTEN KQKNLLQQET NVDKVEPEKG
KKQESSTTNK HSPQNQQLDH STHDSKPTSA AETVSHKRHT RSNSKKSSTR GEERRSQAAN
ETHGKEKSYG SSQGVSSSSS DKGKGPEAIQ SVKNPEKGND LKVVLSYSSD
//
