ID A0A0D2TUV0_GOSRA Unreviewed; 1109 AA.
AC A0A0D2TUV0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=B456_013G045900 {ECO:0000313|EMBL:KJB79368.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB79368.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB79368.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CM001752; KJB79368.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2TUV0; -.
DR EnsemblPlants; KJB79368; KJB79368; B456_013G045900.
DR Gramene; KJB79368; KJB79368; B456_013G045900.
DR OMA; ALYFQYD; -.
DR Proteomes; UP000032304; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16702; RING_CH-C4HC3_MARCH6; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13145:SF0; E3 UBIQUITIN-PROTEIN LIGASE MARCHF6; 1.
DR PANTHER; PTHR13145; SSM4 PROTEIN; 1.
DR Pfam; PF12906; RINGv; 1.
DR SMART; SM00744; RINGv; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 805..830
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..913
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 925..942
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 982..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1017..1036
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 70..131
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
FT DOMAIN 78..125
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1109 AA; 123266 MW; C535EEE15A57EAB1 CRC64;
MEIAPAVPPS HPLDGENPVS SSDDVLADSG KPSPSTSTSS SSSEKDEKAT SSTASTVSLG
AVASRYDPDM EEEEEDVCRI CRNPGDADNP LRYPCACSGS IKFVHQDCLL QWLNHSNARQ
CEVCKHAFSF SPVYAENAPA RLPFQEFVVG MVMKACHILQ FFLRLSFVLS VWLLIIPFIT
FWIWRLAFVR SFGEAQRLFL SHISTTIILT DCLHGFLLSA SIVFIFLGAT SLRDYFRHLR
ELGGQDADRE DEADRNGARA ARRPAGQANR NFAGDANGED AGGAQGVGGA GQMIRRNAEN
VAARWEMQAA RLEAHVEQMF DGLDDADGAE DVPFDELVGM QGPVFHLVEN AFTVLASNMI
FLGVVIFVPF SLGRIILHYV SWLFSSASGP VLSAVMPMTD TTLSLANITL KNALTAVTNL
TSEGQDNSML GQVAEILKAN SSAVGEVSSN KSAPFSADLL KGATIGASRL SDVTTLAIGY
TFIFSLVFFY LGIVTLIRYT RGEPLTMGRF YGIASIVETI PSLFRQFLAA MRHLMTMIKV
AFLLVIELGV FPLMCGWWLD ICTIRMFGKS MSQRVQFFSV SPLASSLIHW VVGIVYMLQI
SIFVSLLRGV LRNGVLYFLR DPADPNYNPF RDLIDDPVNK HARRVLLSVA VYGSLIVMLV
FLPVKFAMKM APSIFPLDIS VSDPFTEIPA DMLLFQICIP FAIEHFKLRT TIKSLLRYWF
TAVGWALGLT EFLLPRPDEN GGQENANVEP GQLDRPQIVQ LGGQEQAMVA FAADDDPNRG
LLASGNSNVL EEFDGDERAD SEYGFVLRIV LLLVVAWMTL LIFNSALIIV PISLGRALFN
AIPLLPITHG IKCNAIAGAR YSIEHIKTKR AAVLFGQISK WSAIVVKSSM LLSIWIFVIP
VLIGLLFELL VIVPMRVPVD ESPVFLLYQD WALGLIFLKI WTRLVMLDHM MPLVDESWRV
KFERVREDGF SRLQGLWVLR EIVFPIIMKL LTALCVPYVL ARGVFPVLGY PLVVNSAVYR
FAWLGCLCFS CLCFCAKRFH VWFTNLHNSI RDDRYLIGRR LHNFGENSEE KQNEAGSYSE
TQISDLRDTG IIQHDREVDV GLRLRRAAN
//
