ID   A0A0D2U0A2_CAPO3        Unreviewed;       998 AA.
AC   A0A0D2U0A2;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Vacuolar protein sorting protein 18 {ECO:0000313|EMBL:KJE88601.1};
GN   ORFNames=CAOG_000232 {ECO:0000313|EMBL:KJE88601.1};
OS   Capsaspora owczarzaki (strain ATCC 30864).
OC   Eukaryota; Filasterea; Capsaspora.
OX   NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE88601.1, ECO:0000313|Proteomes:UP000008743};
RN   [1] {ECO:0000313|Proteomes:UP000008743}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004287};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004287};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004287}.
CC   -!- SIMILARITY: Belongs to the VPS18 family.
CC       {ECO:0000256|ARBA:ARBA00010454}.
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DR   EMBL; KE346360; KJE88601.1; -; Genomic_DNA.
DR   RefSeq; XP_004365103.2; XM_004365046.2.
DR   AlphaFoldDB; A0A0D2U0A2; -.
DR   STRING; 595528.A0A0D2U0A2; -.
DR   EnsemblProtists; KJE88601; KJE88601; CAOG_000232.
DR   GeneID; 14901934; -.
DR   eggNOG; KOG2034; Eukaryota.
DR   InParanoid; A0A0D2U0A2; -.
DR   OrthoDB; 22879at2759; -.
DR   PhylomeDB; A0A0D2U0A2; -.
DR   Proteomes; UP000008743; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16462; RING-H2_Pep3p-like; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR007810; Pep3_Vps18.
DR   PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR23323:SF26; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG; 1.
DR   Pfam; PF05131; Pep3_Vps18; 1.
DR   SUPFAM; SSF75011; 3-carboxy-cis,cis-mucoante lactonizing enzyme; 1.
DR   PROSITE; PS50236; CHCR; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008743};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          48..446
FT                   /note="Pep3/Vps18/deep orange beta-propeller"
FT                   /evidence="ECO:0000259|Pfam:PF05131"
SQ   SEQUENCE   998 AA;  113575 MW;  B9CAED290BFA5B31 CRC64;
     MSLFDQFNSN EIDDIAPMAH MSSETDFDEP IGSSGYISAR LNLEEELPIF SKKLVDYRPP
     HPLVKLVVSN DIIVMALANR SVSRLSLDNA AAIDNVEFTK RLDDSIHNIF LDPFGRHLLI
     SMASGEVYYL HASSKKAKLL SKVKGVIDSV AWNRLATAQE LSTREILIGT NKGMIYEAEI
     EPSEPGIFKD KDEKYFKPVY NIAKDGVQPV TGLRFEQFPS NMQDPKDKRY FVIAATPTRI
     YQFVGVVSTG ETPIFGGLFA NYEITPGFHE MPGDLGYSEL HFFSQLRGLP QSFAWLTGPG
     IYHGSLLYGS QNVGDSVLEQ TSLLNYPTSA TGGSGAPFSM CMTEFHFLLL HRDHLQAVCV
     LNGEAIYEDT VPRKFGALRA LAMDSIKGTI WAYSDSTIFE IGVHKEDRHV WKMFLEKGQF
     ELALQYCHGN LANEDRVLKA QAEHFFAAKK YKLAATYFSR TFSSFEEVAL KFIEKNERDA
     LREYLSRKLE ALKPQDKTQN AMIFTWLVEI FLSQLNSLRD DGEMDKHNSL QEEFRKFLAE
     RVNVALQNTD SKQAKDMDVK PATFYDLLAS HGRMDDLLYF AGLIEDYERI ISHHIQHENC
     VAALDVLTEQ QKNLELYYKF SPVLMQHAPG ETILAWMRNG SLDPRRLIPA LVRYDTYATL
     GAPRSVNHAV KYLEFCVNQL RNTDQAIHNY LVSLYAKLPD EEPMLTFLSN QVQAPCFDLK
     YALRLCTQEQ KKRACVEIYS AMGLYEEAVE LALQVDIELA KENANKPEDD EQLQKKLWLR
     IARYVVEIDN DILRAMAFLT ESNLLKIEDI LPFFPDFATI DDFKDAICSS LEEYNRHIED
     LKTEMYEATE SANFIRTDIQ ELRNKCIIVS GADKCALCNF PLLARQFYVF PCQHSFHADC
     MIQELLPFLN NVQRARVSDL QQRINQERMN AQVLRASGDS SSEVEPTVVI PKGDRYKTEL
     DDIVAGECLF CGDLMVKTID QPFISSVELS TEGASWRL
//