ID A0A0D2UAT0_GOSRA Unreviewed; 791 AA.
AC A0A0D2UAT0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=B456_008G275700 {ECO:0000313|EMBL:KJB52755.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB52755.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB52755.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- FUNCTION: Functions as an E3 ubiquitin ligase.
CC {ECO:0000256|ARBA:ARBA00003861}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM001747; KJB52755.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D2UAT0; -.
DR STRING; 29730.A0A0D2UAT0; -.
DR EnsemblPlants; KJB52755; KJB52755; B456_008G275700.
DR Gramene; KJB52755; KJB52755; B456_008G275700.
DR eggNOG; ENOG502QZPS; Eukaryota.
DR OMA; CAIETEN; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000032304; Chromosome 8.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16655; RING-Ubox_WDSUB1-like; 1.
DR CDD; cd01989; STK_N; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45647; OS02G0152300 PROTEIN; 1.
DR PANTHER; PTHR45647:SF22; U-BOX DOMAIN-CONTAINING PROTEIN 32; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 444..703
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 720..791
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT COILED 319..360
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 471
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 791 AA; 89800 MW; 7E2B783D12398FF6 CRC64;
MGSLVEEIEG DREYDFEDVI FVAVGKNVEK SKTTLDWAVD NFPGKKICVL HVHRPTHVLA
LTADGKLARS KLKQHAVEAF QKLERQRLQE RLDEYLLILD HSGVQADALW IEMDSVEKGI
LEIIARHNIR WLVMGAAADK YYSKKLVELK SKKATFVCQN APVSCHIWFA CKGRLIYTRV
GRQDGSSREI ATPSPPMDSP LRTEQAVMLS ESVLRERSPE PQEDANVVRG NLRPISLYSV
HPNLPSNGVV DTYGSIMLQM DEEEHQGQAS NETDQQLEVS TIDDHNLKQE VFAETMKRWK
EENDAIEAAC KAKALESLCV KEMSRRKEME ELLEREKQEV QKMKDQHDEF IKDLQMVKDQ
RTILESQIVE SQCVVEGLEE KMFSAVELLI SFKKKRDDLR IEHENAIRVL KNLRKLVNGG
DSSFPGSQIL EFSFIEINNA TRDFDPSWKI GEGKYGSVYK GLLRHMNVAI KMLPSYGSQS
LLEFENEVEI LSRIRHPNLV TIIGTCPESR SLVFEYLRNG SLEERLACKN KSPPLPWQTR
IRIASEICSA LIFLHSNKPC IPHGNLKPSK VLLDSNFVSK LIDSGIYRLI PQGKSTDTSA
LSSVYMDPVY LENGEVTRES DVYSFGMILL RLLTGRSALG ILNDVKCSIE TENFNMVLDR
TAGNWPLEEA QLLAHLAIRC CDTQPLDRPD FVSEIWSVLG PMRDSCVNSA SCLEAKELRC
APSHFVCPIF QEVMKDPIIA ADGFTYEADA IRGWLDSGHD RSPMTNLKLE HCNLVPNYAL
LQAIQEWQQQ Y
//
