ID A0A0D2UMH2_GOSRA Unreviewed; 520 AA.
AC A0A0D2UMH2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B456_009G150700 {ECO:0000313|EMBL:KJB57155.1};
OS Gossypium raimondii (New World cotton).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=29730 {ECO:0000313|EMBL:KJB57155.1, ECO:0000313|Proteomes:UP000032304};
RN [1] {ECO:0000313|EMBL:KJB57155.1, ECO:0000313|Proteomes:UP000032304}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23257886; DOI=10.1038/nature11798;
RA Paterson A.H., Wendel J.F., Gundlach H., Guo H., Jenkins J., Jin D.,
RA Llewellyn D., Showmaker K.C., Shu S., Udall J., Yoo M.J., Byers R.,
RA Chen W., Doron-Faigenboim A., Duke M.V., Gong L., Grimwood J., Grover C.,
RA Grupp K., Hu G., Lee T.H., Li J., Lin L., Liu T., Marler B.S., Page J.T.,
RA Roberts A.W., Romanel E., Sanders W.S., Szadkowski E., Tan X., Tang H.,
RA Xu C., Wang J., Wang Z., Zhang D., Zhang L., Ashrafi H., Bedon F.,
RA Bowers J.E., Brubaker C.L., Chee P.W., Das S., Gingle A.R., Haigler C.H.,
RA Harker D., Hoffmann L.V., Hovav R., Jones D.C., Lemke C., Mansoor S.,
RA ur Rahman M., Rainville L.N., Rambani A., Reddy U.K., Rong J.K.,
RA Saranga Y., Scheffler B.E., Scheffler J.A., Stelly D.M., Triplett B.A.,
RA Van Deynze A., Vaslin M.F., Waghmare V.N., Walford S.A., Wright R.J.,
RA Zaki E.A., Zhang T., Dennis E.S., Mayer K.F., Peterson D.G., Rokhsar D.S.,
RA Wang X., Schmutz J.;
RT "Repeated polyploidization of Gossypium genomes and the evolution of
RT spinnable cotton fibres.";
RL Nature 492:423-427(2012).
CC -!- FUNCTION: Might act as an E3 ubiquitin-protein ligase, or as part of E3
CC complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating
CC enzymes and then transfers it to substrates.
CC {ECO:0000256|ARBA:ARBA00003976}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
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DR EMBL; CM001748; KJB57153.1; -; Genomic_DNA.
DR EMBL; CM001748; KJB57154.1; -; Genomic_DNA.
DR EMBL; CM001748; KJB57155.1; -; Genomic_DNA.
DR RefSeq; XP_012444580.1; XM_012589126.1.
DR RefSeq; XP_012444581.1; XM_012589127.1.
DR RefSeq; XP_012444582.1; XM_012589128.1.
DR RefSeq; XP_012444583.1; XM_012589129.1.
DR RefSeq; XP_012444584.1; XM_012589130.1.
DR RefSeq; XP_012444585.1; XM_012589131.1.
DR RefSeq; XP_012444586.1; XM_012589132.1.
DR RefSeq; XP_012444587.1; XM_012589133.1.
DR AlphaFoldDB; A0A0D2UMH2; -.
DR STRING; 29730.A0A0D2UMH2; -.
DR EnsemblPlants; KJB57153; KJB57153; B456_009G150700.
DR EnsemblPlants; KJB57154; KJB57154; B456_009G150700.
DR EnsemblPlants; KJB57155; KJB57155; B456_009G150700.
DR GeneID; 105768885; -.
DR Gramene; KJB57153; KJB57153; B456_009G150700.
DR Gramene; KJB57154; KJB57154; B456_009G150700.
DR Gramene; KJB57155; KJB57155; B456_009G150700.
DR KEGG; gra:105768885; -.
DR eggNOG; KOG1812; Eukaryota.
DR OMA; LNCVECP; -.
DR OrthoDB; 2943236at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000032304; Chromosome 9.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd22582; BRcat_RBR_unk; 1.
DR CDD; cd22584; Rcat_RBR_unk; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF466; RING_U-BOX SUPERFAMILY PROTEIN; 1.
DR Pfam; PF01485; IBR; 2.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000032304};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 202..420
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 206..250
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 520 AA; 59531 MW; 7DDBDE1F4DC169D8 CRC64;
MEDQEVLPDD ISVSLVRGVR AEEDEEDFQS CCEDDEVWKD NEEVAKEEEK KELDEFSVKM
FFKGISLAET GDSSSGFSGI GVVMERSANS PVIQVQKKLD FYVEESVADY LALMDGLTEA
MQNKIRRVYA FTDSALLHDQ ITCEENLDNP LLMALRERIM EHSRNLEEFV LKLVPSTDLL
RPLQLAQVAI GVVSSPAKGD KSLQYCSICF EDKPSLMMIT MKCSHRFCSH CMRTHVDGKL
QSSKVPIRCP QSQCKYYIST AECRSFLPLA SYESLERAQA EANVLHSDGI YCPYPNCSVL
LDPRECLSTR ASSSSQSDNS CVECPVCQRF ICVECGVPWH SSMSCEMYQN LPLEERDAAD
ITLHRLAQNK RWRRCQQCRR MIELAQGCYH MTCWCGHEFC YSCGAEYRDS QQTCQCAFWD
EDNSEGLATH SVQESEQWAW ETFNSLPMLM DAYSDQERSQ LALIQRFLAG GFSLSDHHPY
QSPPRCTDSY VDAMKDLRQL PWLERFVSVI SDNYYEDYIQ
//
