ID A0A0D2VYM0_CAPO3 Unreviewed; 353 AA.
AC A0A0D2VYM0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Zinc-containing alcohol dehydrogenase {ECO:0000313|EMBL:KJE96832.1};
GN ORFNames=CAOG_007094 {ECO:0000313|EMBL:KJE96832.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE96832.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; KE346372; KJE96832.1; -; Genomic_DNA.
DR RefSeq; XP_004343818.1; XM_004343768.2.
DR AlphaFoldDB; A0A0D2VYM0; -.
DR STRING; 595528.A0A0D2VYM0; -.
DR EnsemblProtists; KJE96832; KJE96832; CAOG_007094.
DR GeneID; 14895761; -.
DR eggNOG; KOG0023; Eukaryota.
DR InParanoid; A0A0D2VYM0; -.
DR OMA; FARNEHK; -.
DR OrthoDB; 977199at2759; -.
DR PhylomeDB; A0A0D2VYM0; -.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd05283; CAD1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR047109; CAD-like.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR42683:SF94; DEATH RESISTOR ADH DOMAIN CONTAINING TARGET, ISOFORM C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008743};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 17..349
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 353 AA; 37126 MW; B9FC82E72D909946 CRC64;
MAQASKTVKA FAALQAGQTV SHWEFPAPEL TPHMIAVDVT HCGICHSDIH MMGDEWRGDT
GGSPTTFPLV PGHEVIGTVS ALGSAVTGFK VGQRVGFGAQ GSSCHECALC AKGHEHNCTK
FGGLYDPNHG GYAAHIRADS RFCFAIPDEI PSAHVAPLMC AGVTVFTPLA THLLPPGSRV
GIVGIGGLGH LALQFANKMG YHVTAISTSP SKEAEARSLG AHAFLNSSDA AQMKAHGNAF
PLIIYTASGN IDWNAYMGLV APEGKFVVCG LPEAKIQVSP MYLIGGSKTI VGSLVGGTKA
IKEMLAFSAL HGVRPMIEEV EVGHGADADK VNAALTRVRE NKARYRCVMK YRV
//
