ID   A0A0D2WPN9_CAPO3        Unreviewed;       504 AA.
AC   A0A0D2WPN9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE            EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN   ORFNames=CAOG_003577 {ECO:0000313|EMBL:KJE92658.1};
OS   Capsaspora owczarzaki (strain ATCC 30864).
OC   Eukaryota; Filasterea; Capsaspora.
OX   NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE92658.1, ECO:0000313|Proteomes:UP000008743};
RN   [1] {ECO:0000313|Proteomes:UP000008743}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC         mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC         ChEBI:CHEBI:68623; EC=5.1.3.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00036080};
CC   -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC       {ECO:0000256|ARBA:ARBA00038209}.
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DR   EMBL; KE346364; KJE92658.1; -; Genomic_DNA.
DR   RefSeq; XP_004363305.1; XM_004363248.1.
DR   AlphaFoldDB; A0A0D2WPN9; -.
DR   EnsemblProtists; KJE92658; KJE92658; CAOG_003577.
DR   GeneID; 14898998; -.
DR   eggNOG; ENOG502TDCA; Eukaryota.
DR   InParanoid; A0A0D2WPN9; -.
DR   OMA; CLTLRYN; -.
DR   OrthoDB; 5478068at2759; -.
DR   PhylomeDB; A0A0D2WPN9; -.
DR   Proteomes; UP000008743; Unassembled WGS sequence.
DR   GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:InterPro.
DR   CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR   InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR   InterPro; IPR029767; WecB-like.
DR   NCBIfam; TIGR00236; wecB; 1.
DR   PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR   Pfam; PF02350; Epimerase_2; 1.
DR   SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008743}.
FT   DOMAIN          122..470
FT                   /note="UDP-N-acetylglucosamine 2-epimerase"
FT                   /evidence="ECO:0000259|Pfam:PF02350"
SQ   SEQUENCE   504 AA;  54854 MW;  D3CEF188FC1C5577 CRC64;
     MPSFRLPPFV RKPTVLALVF MLELVVALAL LSSSTGLNGW KLGNPAPDNV DVQLSEQQPG
     ASGDAVSPLP AALAAQLHQL AQHRQNQARR RPLALVFVGT RPEVIKMAPL VHEMQENSVN
     SHVFDTIVVS TGQHREMLAQ TLRGFDLKID LGLSVMQHNQ NLGALFAAVV AQSTAVIASL
     RPEVVLVQGD TSTALACATA AYYERVPVAH VEAGLRSFDF NHPFPEEMNR RAIDSFATFH
     FAPTEYAAEA IRRENTCARN IVVTGNTGVD AVLARLNADP PAAARRLIAQ LQTCTGGACD
     VNDAPPVIIL VTSHRRENLG EPLESICRAV KRIVEDNPVV RVVFPVHLNP NVQKVVFAHL
     KNVDRITLTD PLDYDVLTYL LQEVTIVLSD SGGLQEEAVS IGKPVVLLRQ TTERPEGVYA
     GTVRLAGTNE DRVVSDTQNV IDNLVEYHQR IKGQNVFGDG AASGRIANVL RQYLAADSAQ
     RRKYLAPCTQ EKQAELANVV YGHS
//