ID   A0A0D2WUB5_CAPO3        Unreviewed;       518 AA.
AC   A0A0D2WUB5;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Patatin-like phospholipase domain-containing protein, variant {ECO:0000313|EMBL:KJE96225.1};
GN   ORFNames=CAOG_006579 {ECO:0000313|EMBL:KJE96225.1};
OS   Capsaspora owczarzaki (strain ATCC 30864).
OC   Eukaryota; Filasterea; Capsaspora.
OX   NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE96225.1, ECO:0000313|Proteomes:UP000008743};
RN   [1] {ECO:0000313|Proteomes:UP000008743}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA   Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA   Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PLPL family.
CC       {ECO:0000256|ARBA:ARBA00006104}.
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DR   EMBL; KE346370; KJE96225.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D2WUB5; -.
DR   EnsemblProtists; KJE96225; KJE96225; CAOG_006579.
DR   Proteomes; UP000008743; Unassembled WGS sequence.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07232; Pat_PLPL; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF66; TRIACYLGLYCEROL LIPASE PTL2; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008743}.
FT   DOMAIN          76..267
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
SQ   SEQUENCE   518 AA;  57583 MW;  C1CC9F6EC44E893E CRC64;
     MHTLATKCHK NLAGINSEIL YSHQFVGRTK NIIHEYARTL EAALDVVAAA PEDVLSHDRK
     VKFFRSLEKS YGKSALCLSG GGGQGYYHVG VVRALLDRGL LPAVIAGTSA GALIGSIVCT
     KTDEELRTAL TPDLHAQMTA CAEPLPKRLF RFLKTGNMFE KEPWLVKTRA LIGDWTFEEA
     YLRTGRVFNV TITSANVHSP PLLLNYITAP NVLVYSAVVA SAAIPGLLEA CELLVKNDDG
     SVEPYHVVGE KWTDGGLKTD LPMQSLSHLF NVNYFIVSQV NPHIIPFLYE RKGSAGQPVW
     RAKGVRGGFI TALLEAMLKY DMKKWLIVMK ELELFPMFLG HDWSLIFLQN FAGSVTISPS
     PRFSDYLLIL HDPTRQRMAE YIHRGQTFTY LKVGMIEVAY RTEKKIDTIL QSLGALDMFD
     TILASPIVRE LRLQQEKTNM TIESPPTAPK SPRTVPLFQA TINTPPSNQL TPFESRTDSE
     TTSAAVLPME LGGALLDSGD VDLRQESELI KLRRQTIH
//