ID A0A0D2X3Q4_CAPO3 Unreviewed; 2191 AA.
AC A0A0D2X3Q4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Myosin-VIIa {ECO:0000313|EMBL:KJE94714.1};
GN ORFNames=CAOG_005313 {ECO:0000313|EMBL:KJE94714.1};
OS Capsaspora owczarzaki (strain ATCC 30864).
OC Eukaryota; Filasterea; Capsaspora.
OX NCBI_TaxID=595528 {ECO:0000313|EMBL:KJE94714.1, ECO:0000313|Proteomes:UP000008743};
RN [1] {ECO:0000313|Proteomes:UP000008743}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 30864 {ECO:0000313|Proteomes:UP000008743};
RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., Gargeya S.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KE346367; KJE94714.1; -; Genomic_DNA.
DR RefSeq; XP_004346998.2; XM_004346948.2.
DR STRING; 595528.A0A0D2X3Q4; -.
DR EnsemblProtists; KJE94714; KJE94714; CAOG_005313.
DR GeneID; 14897793; -.
DR eggNOG; KOG4229; Eukaryota.
DR InParanoid; A0A0D2X3Q4; -.
DR OrthoDB; 1094820at2759; -.
DR PhylomeDB; A0A0D2X3Q4; -.
DR Proteomes; UP000008743; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd00124; MYSc; 1.
DR CDD; cd00174; SH3; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR46049; AGAP003327-PA; 1.
DR PANTHER; PTHR46049:SF5; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00784; MyTH4; 2.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00295; B41; 1.
DR SMART; SM00015; IQ; 3.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00139; MyTH4; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51016; MYTH4; 2.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000008743};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 9..704
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1012..1165
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1476..1548
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1672..1826
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1831..2184
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 1979..2015
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 579..601
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 827..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..856
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 102..109
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 2191 AA; 243919 MW; 157EFFCECFEEFEFE CRC64;
MASLLDKSVG AADMTQLPDY KEESLLNNLH VRFQESLVYT YTGSILVAVN PYKSIPIYGN
DVFRRYKGVR IGDLPPHIFA IADGTYTSLF KDGRNQCVVI SGESGAGKTE STKFILQYLA
NLNSKHSLVE EQILMANPIL EAFGNAKTAR NNNSSRFGKF VKVLFGATGA IQGATVSDYL
LEKSRIIYQS QNERNYHIFY NLIAGTTPDQ KAAWCLEPTS AYRYLGNGDG GGLQGRDDKE
EYRTLLEALE LLNFAKDRTH DIFKTVAAVL QIGNIDFSTS DQGGMSCAAV SNAAAFDKVL
KLLEVDAEAL KKSLTFKATE TRGEVFYTPL DQKQAEDTRD ALAKAIYGRQ FSWIVKEINR
NIHAEGTNIG FVGILDIFGF EVFEVNRFEQ FFINYANERL QQYFNQHIFK IEQQEYTSEG
IDWKQIEFID NQPILDLISK KPIGILSLLD EESGFPQCTD VTFVTKVKKQ YEKDPNLLVN
KKAAETFGIA HYAGEVFYRV DGFLEKNRDT LRPALVDTLL ASKLGHLREI FVGFFGEDAA
GSTSSSGTVV SNVKGAKSAG GNAGNKGKVT VGFQFHNSLS DLMQTLFESN PFFVRCIKPN
PSKVPTAFDK TLVMHQLRYS GMMETVRIRS MGYPARRPFQ DFLFRYRVLL PPRTKVAAGS
EPPVIRSIMQ QCGVDPSNPA NAQMGSTKVF YKDHVDKVLE SRREVKFRAN VIRLQSWWRA
RMARKRFLMF RVAIKVIQVF YRGHLMYKAY VKMRRLVIRM QARARGCAMR RRYFIMLEAA
RKAAALEAER LRLAEEARIR AEAEAAAAAA AAAAAAEAAA AAAAEAEAAG LPPPEPIPTV
TVTISPSTTE TTESSAPAAA PAIVASGGDA NTPAPAAKRT RPMSFLQFAN SSTLKRSGSF
ATKNRLTAAE SITLLEMSQS AGELNVEDYR RFKHELIEKE LKRTTELVQK GEISSKEMDR
VMLSLLGSSA MDSVSPAVGP AVGSLLRKQI AGANTFEEFA AAHFNKGLTA TFQPFSLSSS
LLRLSDDLEG VAMLMFDSLN QVIGGATGHP MLEPTGAIQS MIASVLDYPR LGDEMYCQVL
KQISANPNED SRKAAWHVLS NFLGSFPPSV PLAKCVRAFI AKADAAFDFG IIDYKPFCQA
RLDKTCMLLT PRKHAVGALE VQSSSTCSDV ALPINLMDGQ SITVMVDSLM ETHELCAKVA
KAVKMARSDG FAIYFVNGPL ELCIRDNDFV LDVLAAFEAQ AFLTGQLESF SPMFYFKKQC
FMHQLSEKLH LDDPIATRLL YSQVVGAFVT GAIALDSLAI LDVMTQVAAV ETRRDAKTVI
NADWVQANVA REHHKSVTDA RLRDGMAKYK DSTEQALMWL LINRAIAKTP YFASTFRATL
VEAPQDVTPP LKFKKGDEVL LALDTVGFHV CSLDRKSILY TRDYNVIKTH GAKLQEKDAL
WTIQFVRDLQ LTFKLERNDG PAINRKLRVY MEDLHKEARY GLALFDYDAN DATLLPLKKG
DVITVIPEET SDEIQDDEVG EHDDEWIEAE INGKEGFVPR AYVHILLCKP LEDVLGRTET
EVAGPKAAAN ASAAASAGSS EATAPVTKLS AAEEAARIIA EEDAKRESAR AAAEAESLEG
LFKDKKFNLL EYVKENFGDD VEFKKPSVRI RKGNGPSLST WGIGSIAEKI KFSENPIKSA
LHKQMSDADS RQAVNCFRNL MVFMGDMPKR SRGDVHPIAS IINAALAAPT LRDEIYCQII
KQTISNRSKQ QESCGRGWVV MLACTNFFQP SPRFEMYLKK FLRDCAADKK RPFYDVAAIC
EKRLIALKRL GQRATGPSAA ELDSLEHETP LSIKTVFMGT TATKNIHVTN VVNVKDFVGL
VCSRVQIPNP SEWGLWALNL SNPDIEPIPI DNKAYVFDAL NHAAAKWHAP VGVQFRKKFW
LTNEEWKRGG FLAEIMYYQV LDRYLKGHHK VDVDQVAKLA ALQYRVENHD MQAFMSNVCS
VCNNPASKRC SGCKLASYCS RECQQKDWNV HQHVCGHEKL QAGIQWRWGK YIPRELRTFM
RQDEWETRVF AQNKYIKDMD HEAAMQHFLT EVMAWPHIAT NVYNVSKLQD SHGDTYTGVI
ALLSTSKMSF LDPKSKSSLE IIDFKELTNY REQQSDVGAT AAPSLNLKVT DAAGKSRNVR
VNSDEMFDIV QCLELYLEAF NKRNEILAAS S
//
