ID A0A0D3AKE1_BRAOL Unreviewed; 960 AA.
AC A0A0D3AKE1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Replication factor C subunit 1 {ECO:0000256|ARBA:ARBA00020401, ECO:0000256|PIRNR:PIRNR036578};
GN Name=106327509 {ECO:0000313|EnsemblPlants:Bo2g023670.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo2g023670.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo2g023670.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo2g023670.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SUBUNIT: Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can
CC form a complex with RFC1. {ECO:0000256|ARBA:ARBA00011480}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036578}.
CC -!- SIMILARITY: Belongs to the activator 1 large subunit family.
CC {ECO:0000256|ARBA:ARBA00006116, ECO:0000256|PIRNR:PIRNR036578}.
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DR RefSeq; XP_013621122.1; XM_013765668.1.
DR AlphaFoldDB; A0A0D3AKE1; -.
DR STRING; 109376.A0A0D3AKE1; -.
DR EnsemblPlants; Bo2g023670.1; Bo2g023670.1; Bo2g023670.
DR GeneID; 106327509; -.
DR Gramene; Bo2g023670.1; Bo2g023670.1; Bo2g023670.
DR KEGG; boe:106327509; -.
DR eggNOG; KOG1968; Eukaryota.
DR HOGENOM; CLU_003574_4_0_1; -.
DR OMA; LICNERN; -.
DR OrthoDB; 6297at2759; -.
DR Proteomes; UP000032141; Chromosome C2.
DR GO; GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003689; F:DNA clamp loader activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd17752; BRCT_RFC1; 1.
DR CDD; cd18140; HLD_clamp_RFC; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR013725; DNA_replication_fac_RFC1_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012178; RFC1.
DR InterPro; IPR047854; RFC_lid.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF6; REPLICATION FACTOR C SUBUNIT 1; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF08519; RFC1; 1.
DR PIRSF; PIRSF036578; RFC1; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR036578};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR036578};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR036578}; Nucleus {ECO:0000256|PIRNR:PIRNR036578};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141}.
FT DOMAIN 199..282
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..343
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 862..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..891
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 960 AA; 104000 MW; 0CBB0D2F86B3E88A CRC64;
MSDIRKWFMK AHEKGNGNAP KPTKGADAKE TASVKSEQAS EDLETAAARK KTSKYFAKDK
AKAKEEKGVE ELPAKRKLKT DSDDLGKPRP RKAIKVDDDD DDDFEVPSAK KTRDSTPSKK
LKTGSGRGVA TKAVDNDEAD DGEDAQEKDT PVKTGGRGRG GRAASGGGRG GGGRGRGGFM
NFGERKDPPH KGEKEVPDGS PDCLAGLTFV ISGTLDSLER EEAEDLIKRH GGRVTGSVSK
KTTYLLCDED IGGKKSEKAK ELGTEFLTED GLFDMIRSSK PVKKSLPEKT NKSTEKVSAQ
PKISPQKDET RGKPLAKSSP NKAPPPSSPA KGKKKIIQSS LPWTEKYRPK VPNEIVGNQS
LVTQLHNWLS HWHEQFGGSG SKGKGKKLTD ASAKKAVLLS GTPGIGKTTS AKLVSQMLGF
QAVEVNASDS RGKANSNIAK GIGGSNANSV KELVNNEAIA SNIDKSKHPK TVLIMDEVDG
MSAGDRGGVA DLIASIKISK IPIICICNDR YSQKLKSLVN YCLPLNYRKP TKQQMAKRLA
HVAKAEGLEV NDIALEELAE RVNGDIRLAL NQLQYMSLSM SVIKYDDIRQ RLLSSAKDED
ISPFTAVDKL FGYNGGKLRM DERIDLSMSD FDLVPLIVQE NYVNYRPSSA GKDEAKRMDL
LARAAESIAD GDIINVQIRR HRQWQLSLSS CVASSILPAS LMHGSREVLE QGERNFNRFG
GWLGKNSTAG KNTRLLEDLH VHVLASRESS SGRETLRVDY LPLLLNRLTS PLQTLPKDEA
VSEVVEFMNS YSISQEDYDT IMELAKFKGR ANPLEGVAPA VKTALTKKYK ETSKTRMVRA
ADMVQLPGLK KAPKKRIAAM LEPNVESLGD EDGVPLAENE EENESDAEDS EEATNGEKLE
SNLKQLNARG IQVEVDLKGA GSSGGTRKAA GKGRGRGKAA DASAAEKKAT GRGAGAKRKR
//
