ID A0A0D3AZ91_BRAOL Unreviewed; 563 AA.
AC A0A0D3AZ91;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 08-NOV-2023, entry version 37.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106333119 {ECO:0000313|EnsemblPlants:Bo3g001260.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g001260.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo3g001260.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo3g001260.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR RefSeq; XP_013627053.1; XM_013771599.1.
DR AlphaFoldDB; A0A0D3AZ91; -.
DR STRING; 109376.A0A0D3AZ91; -.
DR EnsemblPlants; Bo3g001260.1; Bo3g001260.1; Bo3g001260.
DR GeneID; 106333119; -.
DR Gramene; Bo3g001260.1; Bo3g001260.1; Bo3g001260.
DR KEGG; boe:106333119; -.
DR eggNOG; KOG1087; Eukaryota.
DR HOGENOM; CLU_026748_2_1_1; -.
DR OMA; WQCKDAI; -.
DR OrthoDB; 620063at2759; -.
DR Proteomes; UP000032141; Chromosome C3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR PANTHER; PTHR45898:SF13; TOM1-LIKE PROTEIN 7; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 30..158
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 198..286
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 313..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 62065 MW; 86B2BA622A30FCA7 CRC64;
MTMRPSSSSS ACSASPSLTL SSLSVAVDKA TSELLLTPDW TIIIAICDSL NSNRGHCKDA
IKAVKRRLQH KSSKVQLLTL TLLEAMLKNC GEFVHSHIAE KHVLEDMVKI IVRKKGDFEV
RNKILILLDT WNEAFSARKY PHYNWAYREL IRSGVKFPQR SKEAPLMLEP SSQSSSSSSM
NLMSIGSFKR LDEAMATEIE SLSLSNLESM RTVMDLMSVM VQAVNPSDKS ALKDDLIVDL
VEQCRSNQKK LIQMLTTTSD EDVMARGLEL NDSLQVALAR HDAIASGVSL PMLQAAPETR
DSTSSVLIKT SDADAAALES DPSSSSTSSE SETYEEGDDV KNDFIQLTKS HALLNAEEEE
EETLLLGNNN ENTAETEAKT ECKDLALFDT ATSKSEQDII ELLSLTLSTT ALPSSQTQAP
PNTRFLADDH ILTNSYVVPW AQSQAEAQVP KMAQFVPLGP QFQQQHQQQF SYGYPQAQWN
GVQANNYNDT TLWGQGVSEN KVFERNLQYS NSFPARGGAG GASGAEVEGQ AQQQPQRQYV
PPYKLFEDLN VFWKGDGGVR SSK
//
