ID A0A0D3B1Z0_BRAOL Unreviewed; 736 AA.
AC A0A0D3B1Z0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Mechanosensitive ion channel protein {ECO:0000256|PIRNR:PIRNR017209};
GN Name=106332687 {ECO:0000313|EnsemblPlants:Bo3g013720.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g013720.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo3g013720.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo3g013720.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|PIRNR:PIRNR017209}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013626616.1; XM_013771162.1.
DR AlphaFoldDB; A0A0D3B1Z0; -.
DR STRING; 109376.A0A0D3B1Z0; -.
DR EnsemblPlants; Bo3g013720.1; Bo3g013720.1; Bo3g013720.
DR GeneID; 106332687; -.
DR Gramene; Bo3g013720.1; Bo3g013720.1; Bo3g013720.
DR KEGG; boe:106332687; -.
DR eggNOG; KOG4629; Eukaryota.
DR HOGENOM; CLU_013552_1_0_1; -.
DR OMA; MDHCINT; -.
DR OrthoDB; 11155at2759; -.
DR Proteomes; UP000032141; Chromosome C3.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR016688; MscS-like_plants/fungi.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR31618; MECHANOSENSITIVE ION CHANNEL PROTEIN 5; 1.
DR PANTHER; PTHR31618:SF17; MECHANOSENSITIVE ION CHANNEL PROTEIN 9; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR PIRSF; PIRSF017209; Memb_At2g17000_prd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR017209};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT TRANSMEM 174..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 544..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 562..625
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT REGION 1..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 736 AA; 83348 MW; E4B97D684C625D2A CRC64;
MAERKITNGG DIVINVPEKQ VSKDSAASPS SNAAASPKPN PGTVKLEPLS IPQPEIYKLS
GSVHKPPKTP SPNTKGLTRR RSVYSKSNSR FGQQQSYRYD KTIVEENGGT TPKEHFGAAS
FSRASFNRAS QSNRSNRSIS SALSKVSEDE ADENEEIYKK VKLHQGKRSV MNPLALLELL
IFFAILCLLV VSLTIDTVKE HCIWGLEVWK WCVLVMVTLS GMFVTNWFMH IVVFIIERNY
LLRKKVLYFV HGLKKNVQVF IWFSLVLVAW VFLFDDDDAR SRKTKKFLDK ITWTIVSLLV
GSIIFLVKTF ALKVLASKFN VRNFFERIQE SVFHQYILQT LSGPPLIEEA EKVGREPSTG
HLSFTSTNGT VKEKKVLDMG KVHKMKQEKV SAWTMRVLME AVGASGLSTI SNTLDEVTHR
KEKTDKEITN EMEAVAAAYD IFNNVAQPNS SYIEEDDLLR FMIKEEVDLV LPLIDGGETG
KITRNAFTEW VINVYTSRKA LGHSLNDTKT AVRQVDKLIT GVMSVITFIV WLVLLDIATT
KFLLVFSTQF VGLAFMIGST CKNIFESFVF VFVMHPYDVG DRCVIDGIIL LVEEIHLLTT
VFLKIDNEKV FYPNATLVSK PISNFYRSPD MGDAVEFSIA FSTPAAKIAT LKEKIAEYLV
QNPHNWYPEP LLMVKAIENV NKLNLNVLFQ HTINFQNFAE KNLRRTEMVI TLKRILEELE
IDYTLLPQQV HLTGQK
//
