ID A0A0D3BED9_BRAOL Unreviewed; 3890 AA.
AC A0A0D3BED9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo3g093840.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g093840.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo3g093840.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo3g093840.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 109376.A0A0D3BED9; -.
DR EnsemblPlants; Bo3g093840.1; Bo3g093840.1; Bo3g093840.
DR Gramene; Bo3g093840.1; Bo3g093840.1; Bo3g093840.
DR eggNOG; KOG0889; Eukaryota.
DR HOGENOM; CLU_000129_1_0_1; -.
DR OMA; CETCPSH; -.
DR Proteomes; UP000032141; Chromosome C3.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd05163; PIKK_TRRAP; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR046807; Tra1_central.
DR InterPro; IPR046805; Tra1_ring.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF1; TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF20175; Tra1_central; 1.
DR Pfam; PF20206; Tra1_ring; 1.
DR SMART; SM01343; FATC; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032141}.
FT DOMAIN 2652..3195
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 3518..3845
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 3858..3890
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
FT REGION 1993..2039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2282..2301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3219..3282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1997..2021
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3231..3282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3890 AA; 439384 MW; 6BA6CE6AF4D293B5 CRC64;
MSPIQNFEQH SRRLVDPDLP IQTRLEMVVE VRDSLEIAHT AEYLNFLKCY FPAFSVILLR
ITKPQFVDNP EHKLRNIVVE ILNRLPHSEV LRPFVQDLLK VAMQVLTTDN EENGLICIRI
IFDLLRNFRP TLENEVQPFL DFVCKIYQVF RFTVSHFFDN VKMEEVKVKP VETSASSDQS
SLTPVAPVGN GQLNPSTRSF KIITESPLVV MFLFQLYSRL VQTNIPHLLP LMVAAISVPG
PENVPSHLKP QFIELKGAQV KTVSFLTYLL KSCAEYIRPH EESICKSIVN LLVTCSDSAS
IRKELLVSLK HVLGTDFKRG LFPLIDTLLD ESVLVGTGRA CFESLRPLAY SLLAEIVHHV
RGDLSLSQLS RIIYLFSRNM HDSTLSVSIH TTCARLMLNL VEPIFEKAVD QQSMDEARIL
LGRILDAFVG KFSNFKRTIP QLMEEGEVGK DRVTLRAKLE LPVQVPVEHS KEVNDYKNLI
KTLVMGMKTI IWSITHAHLP RPQGLNPQAL ASQSSAPQGF KGMREDEVWK ASGVLKSGVH
CLALFKEKDE EKEMLSLFSQ ILAIMEPRDL MDMFSLCMPE LFECMINNNQ LVQIFAALLQ
APKVYKPFAD VLINLLVSSK LDVLKNPESD ATKLVLHLFR CIFGAVTKAP SDFERILQHH
VPAIMEVCMK SATEVEKPLG YMQLLRTVFR GLAGCKYELL LRDLIPMLLP CLNMLLTMLE
GPAGEDMKDL LLELCLTLPA RLSSLLPYLP RLMKPLVFCL RGSDELVSLG LRTLEFWVDS
LNPDFLEPSM ANVMSEVILA LWSHLRPVPY PWGGKALQIL GKLGGRNRRF LKEPLTLECK
DNPEHGLRLV LTFEPSTPFL VPLDKFINLA VVAVIQKNQG IDIYYRKQAL KFLRVCLLSQ
LNLPGCVTDV GQTSRQLSTL LRSSVDSSLH RSESGEMKAD LGVKTKTQLM AEKSIFKTLL
VTILAASSDL DLSDSDDDFV VNICRHFAII LHIDYTSSNA SSSTGSLGGS VISASSRSKG
NRSSNLKQLD PLIFLDALVD VLADENRLHA KAALNALNVF SETLLFLARV KHADVLMARG
GNNASMIVSS PSTNPVYSPH PSVRIPVFEQ LLPRLLHGCY GSTWQAQMGG VMGLGALVGK
VNVETLCIFQ VKIVRGLVYV LKRLPVYASK EQEETSQVLM QILRVVNNVD EANSEARRKS
FQDVVEYLAT ELFNPNASIP VRKNVQNCLA LLASRTGSEV TELLEPLYQL LLQPLIMRPL
RSKTVDQQVG TVSALNFCLA LRPPLLKVTP ELVNFLQEAL QIAEADETVW AVKLMNPKVL
TSLNRLRTAC IELLCTTMAW TDFRTQTHNE LRAKIISMFF KSLTCRAPEI VAVAKEGLRQ
VINQQRMPKE LLQSSLRPIL VNLAHTKNLS MPLLQGLARL LELLSNWFNV TLGGKLLEHL
KKWLEPEKLA QSQKSWKAGE EPKIAAAIIE LFHLLPHAAS KFLDELVTLT IDLEAALPPG
QVYSEINSPY RLPLTKFLNR YASLAVDYFL SRLSEPKYFR RFMYIIRSDA GQPLREELAK
SPQKILSYAF PEILPKLDAT MSMAASTPPA TSCGDENIVA VKSESSSTAP TKANVASDAY
FQGLYLMKTM VKLIPSWLQS NRSVFDTLVL IWKSPSRISR LQNEQELNLV QVKESKWLVK
CFLNYLRHEK SEVNVLFDIL SIFLFHSRID YTFLKEFYII EVAEGYPPNM KRALLLHFLD
LFYSKQLGHD HLVQAMQMLI LPMLSYAFQN GQTWEVIDPD IVKTIVERLL DPPEEVSAEY
DEPLRIELLQ LATLLLKYLQ SDLVHHRKEL IKFGWNHLKR EDSASKQWAF VNVCHFLDAY
QAPEKIILQV FVALLRTCQP ENKMLVKQAL DILMPALPKR LPLGDSRMPI WIRYTKKILV
EEGHSIPNLI HIFLLVVRHS DLFYSCRAQF VPQMVNSLSR LGLPYNTTAE NRRLAIELAG
LVVSWERQRQ KEMKMVADTD GTSQATDELH TSSGADPKRS TDGSATSEDP SKRVKIEPGL
QSICVMSPGG ASSIPNVETP GSATQPDEEF KPNAAMEEMI INFLIRVTLV IEPKDRETNT
MYNQALDLLS QALEVWPNAN VKFNYLEKLL SSMPPSQSSD PSTALAQGLD VMNKVLEKQP
HLFIRNNINQ ISQILEPCFK TKMLDAGKSL CSVLKMVFTA FPLDAANTPP DIKLLYQKVN
ELINKHVSAV TAPQASGEDN SFGSISFVLL VIKTLAKVHK NFVDSYVVVR ILQRLARDLG
SAVGSHPRQG TRADSDSAVT SSRQSADVGS VICNIKSVLE LIDETVMLIP DCKRSVTQIL
NTLLSEKGID ASVLLCILDM IKRWVEDDVS KTGASGMSGS FLTQKDIVAF LNKLSYLDKQ
QFSSDALEEW DQKYLQLLYG LCADSTKYPL ALRQEVSLKV ERHFMLGLRA RDPEMRRKFF
LLYHESLGKN LFSRLQYIIQ IQDWEALSDV FWLKQGLDLL LAILVEDKPI SLAPNSARVP
ALLPSDNPGL QHQPLATLEG PEEVASMFDN IVMKHAQFLS ATSKLQVADV VIPLRELAHT
DANVAYHLWV LVFPIVWVTL LKEEQVALAK PMISLLSKDY HKKQQGHRPN VVQALLEGLQ
LSHPQPRMPS ELIKYIGKTY NAWHLALALL ESHVMLFMND SKCAESLAEL YRLLNEEDMR
YGLWKKRSIT AETRAGLSLV QHGFWQRAQS LFYQAMVKAT QGTYNNTVPK AEMCMWEEQW
LHCAAQLGQW DALVDFGKSI ENYEILLDSL WKLPDWAYLK DHVIPKAQVE ETPKLRLVQA
YFALHDRNSG GVGDAENIVG KGVDLALEQW WQLPEMSVHA RVPLLQQFQQ LVEVQESARI
HVDIANGNKV SGNVAVGAPG NRYADLKDIL ETWRLRTPNE WDSMPVWYDM LQWRNEMYNV
VIEAFKDFAT SNSPLHHLGF RDKAWNVNKL ARIARKQELY DVCVQILEKM YGHSTMEVQE
AFVKIREQAK AYLEMKGERA SGLNLINSTN LEYFPDKIKA EIFRLKGDFH LKLNDTEGAN
IAYSNAITLF KNLPKGWISW GNYCDMAYQE TQDEIWLEYA VSCFLQGIRF GVSNSRSHIA
RVLYLLSFDT ANESVGRVFD KHLEQVPHWV WLSWIPQLLL SLQRTEAPHC KLVLLKIAAV
FPQALYYWLR TYLLERRDAV NKSELGRLVL AQRMQQNASG VAGHGGGNLP SETHQGAQVG
GASGTHDSGN PHGQESERST AENNAHPGND QSMHQSSSTI NENTARQNGA SLAMSAAGAF
DAAKDIMEAL RSKHNNLASE LEVIFVLFVY VSSMFIQIAL NCDESFLFDL DDLSKYLPFQ
VLLTEIGSRF VTLPEERLLA VVNALLHRCY KYPTATTAEV PQPLKKELSG VCRACFSADA
VTKHVEFVKE YKQDFERHLD PESTTTFPAT LAELTTRLKK WKNILQSNVE DRFPAVLRLE
DESRVLRDFN VVDVEIPGQY FADQEVAPDH TVKLDRVGAD VPIVRRHGSS FRRLTLIGSD
GSQKHFIVQT SLTPNARSDE RILQLFRVMN QMFDKHKESR RRHIGIHTPI IIPVWSQVRM
VEDDVMYNTF LEVYENHCAR NDREADLPIS HFKEQLNQAI SGQVSAEAIG DLRLQAYSDI
TKTLVNDSIF SQYMYKTLMS GSHMWAFKKQ FAVQLAVSSF MSFMLQIGGR SPNKVLFAKN
TGKMFQTDFH PAYDANGMIE FNEPVPFRLT RNMQAFFSQF GVEGLLMSSM CSAAQAVISS
KQNDYLRYQL AMFFRDELLS WFGRRPLGMP IPPVGGIATL NSAELKDKVN SNVKDVIGRI
RGIAPQYFSE EDENIVEPPQ SVQRGVNELV EAALSPRNLC MMDPTWHPWF
//
