ID A0A0D3BJ61_BRAOL Unreviewed; 471 AA.
AC A0A0D3BJ61;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=CNNM transmembrane domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106336478 {ECO:0000313|EnsemblPlants:Bo3g149170.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo3g149170.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo3g149170.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo3g149170.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013630767.1; XM_013775313.1.
DR AlphaFoldDB; A0A0D3BJ61; -.
DR STRING; 109376.A0A0D3BJ61; -.
DR EnsemblPlants; Bo3g149170.1; Bo3g149170.1; Bo3g149170.
DR GeneID; 106336478; -.
DR Gramene; Bo3g149170.1; Bo3g149170.1; Bo3g149170.
DR KEGG; boe:106336478; -.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_0_0_1; -.
DR OMA; NTFESNA; -.
DR OrthoDB; 180399at2759; -.
DR Proteomes; UP000032141; Chromosome C3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064:SF75; CNNM TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 31..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..212
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 231..291
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 441..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 51442 MW; E9633F48C96D958B CRC64;
MHPFNAMMAA RMLTAVGKSN GLESETIPFG SLWWSIYAGV SCFLVLFAGI MSGLTLGLMS
LSLVDLEILQ RSGSPKEKKQ SAAIFPVVQK QHQLLVTLLL FNALAMEGLP IYLDKIFNEY
VAIILSVTFV LFVGEVIPQA ICSRYGLAVG ANLVWLVRIL MILSYPISFP VAKMLDWVLG
HGDPLFRRAQ LKALVSIHGE AAGKGGELTH DETTIISGAL DLTAKTAREA MTPIESIFSL
DINSKLDWEA MYKIQTRGHS RIPVYSENPK NVVGLLLVKS LLTVRPESDT LVSTVGIRHI
PRVPADMPLY DILNEFQKGS SHMAAVVKVN VKRKGSLSTL LEEENTNDSK LTTPLLLKRE
GNQDNVVVDI DKISNSGFSH TSEEIEDGEV IGVITLEDVF EELLQEEIVD ETDEFVDVHK
RIRVATVAAV AISSLARAPS SRRLLGQKGT GGPKTPKASS TTPKTGQDKP I
//
