ID A0A0D3BSQ1_BRAOL Unreviewed; 1007 AA.
AC A0A0D3BSQ1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=26S proteasome non-ATPase regulatory subunit 1 homolog {ECO:0000256|PIRNR:PIRNR015947};
GN Name=106342345 {ECO:0000313|EnsemblPlants:Bo4g045670.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo4g045670.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo4g045670.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo4g045670.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- FUNCTION: Acts as a regulatory subunit of the 26S proteasome which is
CC involved in the ATP-dependent degradation of ubiquitinated proteins.
CC {ECO:0000256|PIRNR:PIRNR015947}.
CC -!- SUBUNIT: Component of the 19S regulatory particle (RP/PA700) base
CC subcomplex of the 26S proteasome. The 26S proteasome is composed of a
CC core protease (CP), known as the 20S proteasome, capped at one or both
CC ends by the 19S regulatory particle (RP/PA700).
CC {ECO:0000256|PIRNR:PIRNR015947}.
CC -!- SIMILARITY: Belongs to the proteasome subunit S1 family.
CC {ECO:0000256|ARBA:ARBA00006308, ECO:0000256|PIRNR:PIRNR015947}.
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DR RefSeq; XP_013636707.1; XM_013781253.1.
DR AlphaFoldDB; A0A0D3BSQ1; -.
DR STRING; 109376.A0A0D3BSQ1; -.
DR EnsemblPlants; Bo4g045670.1; Bo4g045670.1; Bo4g045670.
DR GeneID; 106342345; -.
DR Gramene; Bo4g045670.1; Bo4g045670.1; Bo4g045670.
DR KEGG; boe:106342345; -.
DR eggNOG; KOG2062; Eukaryota.
DR HOGENOM; CLU_002323_0_0_1; -.
DR OMA; QFLYIHN; -.
DR OrthoDB; 151732at2759; -.
DR Proteomes; UP000032141; Chromosome C4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:UniProtKB-UniRule.
DR GO; GO:0030234; F:enzyme regulator activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042176; P:regulation of protein catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR016642; 26S_Psome_Rpn2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002015; Proteasome/cyclosome_rpt.
DR InterPro; IPR048570; PSMD1_RPN2_N.
DR InterPro; IPR040623; RPN2_C.
DR PANTHER; PTHR10943; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR10943:SF18; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 HOMOLOG; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF01851; PC_rep; 1.
DR Pfam; PF18004; RPN2_C; 1.
DR Pfam; PF21505; RPN2_N; 1.
DR PIRSF; PIRSF015947; 26S_Psome_Rpn2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000256|PIRNR:PIRNR015947};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 783..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 8..354
FT /note="26S proteasome non-ATPase regulatory subunit 1/RPN2
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21505"
FT DOMAIN 799..962
FT /note="26S proteasome regulatory subunit RPN2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18004"
FT REGION 856..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 965..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..893
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..991
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 109160 MW; 43C43F05F5596D78 CRC64;
MAAAMVSSAG GLLAMLNEPQ PTLKHHALSH LNNLVDRFWP EISTSVPIIE SLYEDEEFDL
HQRQLAALLV SKVFYYLGEL NDSLSYALGA GALFDVSEDT DYVHTLLAKA IDEYAILRSK
AVESSEMVDI DPRLEAIVER MLGKCITDGK YQQSMGIAIE CRRLDKLEEA ITKSDNVEGT
LTYCINVSHS FVNRREYRHE VLSLLVEVYQ KLPSPDYLSI CQCLMFLDEP QGVATILEKL
LRSDSKDDAL LALQIAFDLV ENEHQAFLLS VRDRLPAPKT RPVEVAQAVE TTATTNENLS
GDVLMADDTP VTPAQTVVHE TDPVDATYAE RLTKIKGILS GETSIQLTLQ FLYIHNKSDL
LILKTIKQSV EMRNSVCHSA TIYANAIMHA GTTVDTFLRE NLDWLSRATN WAKFSATAGL
GVIHRGHLQQ GRSLMAPYLP QGGAGGGGSP YSEGGALYAL GLIHANHGEG IKQFLRDSLR
NTNVEVIQHG ACLGLGLSAL GTADEEIYDD VKSVLYTDSA VAGEAAGISM GLLLVGTATE
KASEMLAYAH ETQHEKIIRG LALGIALTVY GREEGADTLI EQMTRDQDPI IRYGGMYALA
LAYCGTANNK AIRQLLHFAV SDVSDDVRRT AVLALGFVLY SDPEQTPRIV SLLSESYNPH
VRYGAALAVG ISCAGTGLSE AISLLEPLTS DVVDFVRQGA LIAMAMVMVQ ISEASDSRVG
AFRRQLEKII LDKHEDTMSK MGAILASGIL DAGGRNVTIR LLSKTKHDKV TAVIGLAVFS
QFWYWYPLVY FISLAFSPTA FIGLNYDLKV PKFEFMSHAK PSLFEYPKPT TVPTSNTAAK
LPTAVLSTSV KAKARAKKEA EQKANAEKAS GAEKSVSESG SGKGKEAADK EGDSMQVDGT
ATVEKKAAEP EAAFEILVNP TRVVPAQEKY IKLLEDSRYV PVKLAPSGFV LLKDLREHEP
EVLSLTDAPT SAASPATGAA AATQGTTASA MAVDDEPQPP QAFEYAS
//
