ID A0A0D3C4L6_BRAOL Unreviewed; 548 AA.
AC A0A0D3C4L6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=CBS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106341307 {ECO:0000313|EnsemblPlants:Bo4g186320.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo4g186320.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo4g186320.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo4g186320.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR RefSeq; XP_013635555.1; XM_013780101.1.
DR AlphaFoldDB; A0A0D3C4L6; -.
DR STRING; 109376.A0A0D3C4L6; -.
DR EnsemblPlants; Bo4g186320.1; Bo4g186320.1; Bo4g186320.
DR GeneID; 106341307; -.
DR Gramene; Bo4g186320.1; Bo4g186320.1; Bo4g186320.
DR KEGG; boe:106341307; -.
DR eggNOG; ENOG502QVK2; Eukaryota.
DR HOGENOM; CLU_009026_3_0_1; -.
DR OMA; PETACME; -.
DR OrthoDB; 671798at2759; -.
DR Proteomes; UP000032141; Chromosome C4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17781; CBS_pair_MUG70_1; 1.
DR CDD; cd17782; CBS_pair_MUG70_2; 1.
DR CDD; cd06409; PB1_MUG70; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 2.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR PANTHER; PTHR13780; AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR13780:SF133; CBS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00571; CBS; 4.
DR Pfam; PF00564; PB1; 1.
DR SMART; SM00116; CBS; 4.
DR SMART; SM00666; PB1; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 2.
DR PROSITE; PS51371; CBS; 4.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 520..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..118
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 126..181
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 229..288
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 296..352
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 414..498
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 59284 MW; CB0D618DFBCB38F3 CRC64;
MTSSGKRSTR RGSSSASKKP VLQPQDSGSS SLNENPSPKP GSPLPEPVSS NTERTVKTLR
LSKAITIPEG TTVFDACRRM ARKKVDAVLL TDSSALLSGI VTDKDIATRV IAEGLRPEHT
LVSKVMTRNP IFVTSESLAI EALEKMVQGK FRHLPVVENG EVIALLDITK CLYDAISRME
KAAEQGSVLA AAAVEDIERQ WGSDNTSAPY PFVETLRDRM FKPALSTIIT EHSKVAIASP
SDPVFVASKK MRDLRVNSVI ITVGNKVQGI LTSKDILMRV VAKNLSPELT LVEKVMTPNP
ETACMETTIV DALHVMHDGK FLHLPVLDKD GYVVACVDVL QITHAAISTV ESSPGAVSDM
ANTMMQKFWD SALSLDPHPP EDYETHSDLS STMLLNSEGG GGVDSGKLQS CGSVSLFAFK
FEDRKGRVHR FESTGESFEE VMSGVVQRCD DGDVGVQIMY EDDEGDKVLI SRDSDVVAAV
AFARSLGHKV LRLHVDFTEV VSVERSGDLS EGSCGDGCGW VWWQAGVVAG AVVLTSLGFL
VYLKRSKK
//
