ID A0A0D3CMA5_BRAOL Unreviewed; 496 AA.
AC A0A0D3CMA5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Galactokinase {ECO:0008006|Google:ProtNLM};
GN Name=106296154 {ECO:0000313|EnsemblPlants:Bo5g143380.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo5g143380.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo5g143380.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo5g143380.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC {ECO:0000256|ARBA:ARBA00006566}.
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DR RefSeq; XP_013587676.1; XM_013732222.1.
DR AlphaFoldDB; A0A0D3CMA5; -.
DR STRING; 109376.A0A0D3CMA5; -.
DR EnsemblPlants; Bo5g143380.1; Bo5g143380.1; Bo5g143380.
DR GeneID; 106296154; -.
DR Gramene; Bo5g143380.1; Bo5g143380.1; Bo5g143380.
DR KEGG; boe:106296154; -.
DR eggNOG; KOG0631; Eukaryota.
DR HOGENOM; CLU_017814_6_2_1; -.
DR OMA; GFHDTYF; -.
DR OrthoDB; 177392at2759; -.
DR Proteomes; UP000032141; Chromosome C5.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR Gene3D; 1.20.1440.340; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.3170; -; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019741; Galactokinase_CS.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR PANTHER; PTHR10457:SF7; N-ACETYLGALACTOSAMINE KINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00106; GALACTOKINASE; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 38..86
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 151..217
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 391..465
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 496 AA; 54262 MW; 741974717024B3B6 CRC64;
MAKQEEVTVP IFTSLDPVYG EGSQLQEANS RFDALKSKFN QAFGASPQLF ARSPGRVNLI
GEHIDYEGYS VLPMAIRQDT IIAIRKREGQ NELRIANVNE KYSMCTYPAD PLQEIDLKNH
KWGHYFICAY KGFHEFAKSK GVNVDSPVGL DVVVDGIVPT GSGLSSSAAF VCSSTIAIMA
VFGESFEKKE LAQLTCECEQ HIGTQSGGMD QAISIMAKTG FAELIDFNPV RATDVKLPDG
GSFVIAHSLA ESQKAVTAAT NYNNRVVECR LASIILGIKL GMEPKEAISK VKTLSDVEGL
CVSFAGDRGS SDPVLAVKEY LKEEPYTAEE IERIVEEKLP SILNNDPTSL AVLNAATHFK
LHQRAAHVYS EARRVHGFKD TVYSNLSDEE KLKKLGDLMN DSHYSCSVLY ECSCPELEEL
VKVSRENGAL GARLTGAGWG GCTVALVKES GVSQFIAAVK EKYYKKRIEK GVVKEEDMEL
YLFASKPSSG AAIFNF
//
