ID A0A0D3CX02_BRAOL Unreviewed; 795 AA.
AC A0A0D3CX02;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Protein ROOT HAIR DEFECTIVE 3 homolog {ECO:0000256|HAMAP-Rule:MF_03109};
DE EC=3.6.5.- {ECO:0000256|HAMAP-Rule:MF_03109};
DE AltName: Full=Protein SEY1 homolog {ECO:0000256|HAMAP-Rule:MF_03109};
GN Name=106299143 {ECO:0000313|EnsemblPlants:Bo6g088150.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo6g088150.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo6g088150.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo6g088150.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- FUNCTION: Probable GTP-binding protein that may be involved in cell
CC development. {ECO:0000256|HAMAP-Rule:MF_03109}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|HAMAP-Rule:MF_03109}; Multi-pass membrane protein
CC {ECO:0000256|HAMAP-Rule:MF_03109}.
CC -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_03109}.
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DR RefSeq; XP_013590730.1; XM_013735276.1.
DR AlphaFoldDB; A0A0D3CX02; -.
DR STRING; 109376.A0A0D3CX02; -.
DR EnsemblPlants; Bo6g088150.1; Bo6g088150.1; Bo6g088150.
DR GeneID; 106299143; -.
DR Gramene; Bo6g088150.1; Bo6g088150.1; Bo6g088150.
DR KEGG; boe:106299143; -.
DR eggNOG; KOG2203; Eukaryota.
DR HOGENOM; CLU_011270_1_0_1; -.
DR OMA; ATSVECC; -.
DR OrthoDB; 1606at2759; -.
DR Proteomes; UP000032141; Chromosome C6.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR CDD; cd01851; GBP; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_03109; Sey1; 1.
DR InterPro; IPR030386; G_GB1_RHD3_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008803; RHD3/Sey1.
DR InterPro; IPR046758; Sey1/RHD3-like_3HB.
DR PANTHER; PTHR45923:SF15; PROTEIN ROOT HAIR DEFECTIVE 3 HOMOLOG; 1.
DR PANTHER; PTHR45923; PROTEIN SEY1; 1.
DR Pfam; PF05879; RHD3_GTPase; 1.
DR Pfam; PF20428; Sey1_3HB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51715; G_GB1_RHD3; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|HAMAP-Rule:MF_03109};
KW GTP-binding {ECO:0000256|HAMAP-Rule:MF_03109};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_03109};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_03109};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_03109};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transmembrane {ECO:0000256|HAMAP-Rule:MF_03109};
KW Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_03109}.
FT TOPO_DOM 1..678
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03109"
FT TOPO_DOM 700..702
FT /note="Lumenal"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03109"
FT TOPO_DOM 724..795
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03109"
FT DOMAIN 38..253
FT /note="GB1/RHD3-type G"
FT /evidence="ECO:0000259|PROSITE:PS51715"
FT REGION 758..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 48..55
FT /ligand="GTP"
FT /ligand_id="ChEBI:CHEBI:37565"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03109"
SQ SEQUENCE 795 AA; 88450 MW; D7A1973C81926EE3 CRC64;
MMDKSEGNCS VQLIDGDGTY NVSGIDHFIK EVKLGECGLS YAVVSIMGPQ SSGKSTLLNN
LFGTNFMEMD AFKGRSQTTK GIWLARCAGI EPCTLVMDLE GTDGRERGED DTAFEKQSAL
FALAISDIVL INMWCHDIGR EQAANKPLLK TVFQVMMRLF SPRKTTMLFV IRDKTRTPLE
NLEPVLREDI QKIWDSVPKP EAHKETPMSD FFNVEVVALS SYEEKEEQFK EQVASLRQRF
MHSIAPGGLA GDRRGVIPAS GFAFSADQIW RVIKENKDLD LPAHKVMVAT VRCEEISNEK
FAHFITNEDW RKLDEEVQAG PVSGFGKRLT SILGSCLSEY DGEATFFDEG VRSSKRHQLE
EKLLQLVNPA FQDVLGHIRW GMLEKFKASF DKALEIGEGF SSASTTWLKA CMDQFDEECA
GAIIEQANWD TAKVREKLVR DIEAHVSSVR TSKLSELTSQ YETKLHQALS EPVEALLEGA
SDQTWTTVKK LHGRETETAV SGFSSALAAF DIEEETREKM VKSLQEYSRG VIESKAKEEA
GRVLMRMKDR FATIFSNDAD SMPRVWTGNE DLRAITKAAR SASLKLLSVM AVMRLGDETD
NIEKTLTVAL LDSTPSKKSI TASDPLASST WDEIPSSRTL ITPVHCKSIW RQFKTETEYT
VTQAISAQEA NKRGSNWLPP PWAIFALIIL GFNEFMTLLR NPLYLGVLFV GFLLLKALWT
QLDIPGEFRN GALPGIISIS AKFVPTIMNL VKNLAAQGEA PPAANPENRR PSNNTSSNAS
STDNPTEHKS ASKTD
//
