ID A0A0D3DB24_BRAOL Unreviewed; 446 AA.
AC A0A0D3DB24;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Probable magnesium transporter {ECO:0000256|RuleBase:RU363078};
GN Name=106305799 {ECO:0000313|EnsemblPlants:Bo7g083810.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo7g083810.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo7g083810.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo7g083810.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- FUNCTION: Acts as a Mg(2+) transporter. Can also transport other
CC divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but
CC to a much less extent than Mg(2+). {ECO:0000256|ARBA:ARBA00025284,
CC ECO:0000256|RuleBase:RU363078}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738,
CC ECO:0000256|RuleBase:RU363078}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363078};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363078}. Early
CC endosome {ECO:0000256|RuleBase:RU363078}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NIPA (TC 2.A.7) family.
CC {ECO:0000256|ARBA:ARBA00007001, ECO:0000256|RuleBase:RU363078}.
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DR RefSeq; XP_013597643.1; XM_013742189.1.
DR AlphaFoldDB; A0A0D3DB24; -.
DR EnsemblPlants; Bo7g083810.1; Bo7g083810.1; Bo7g083810.
DR GeneID; 106305799; -.
DR Gramene; Bo7g083810.1; Bo7g083810.1; Bo7g083810.
DR KEGG; boe:106305799; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_054115_0_0_1; -.
DR OMA; FQEYQVL; -.
DR OrthoDB; 948at2759; -.
DR Proteomes; UP000032141; Chromosome C7.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF75; MAGNESIUM TRANSPORTER-RELATED; 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU363078};
KW Endosome {ECO:0000256|RuleBase:RU363078};
KW Ion transport {ECO:0000256|RuleBase:RU363078};
KW Magnesium {ECO:0000256|RuleBase:RU363078};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363078};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363078};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363078}; Transport {ECO:0000256|RuleBase:RU363078}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 58..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 82..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 108..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 227..244
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT TRANSMEM 291..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363078"
FT REGION 314..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49046 MW; C94C4519F7CE0FA5 CRC64;
MGEWVIGAFI NIFGSVAINF GTNLLKLGHN ERERLALQDG GGGKTPLKPI IHFQTWRVGI
LVFLLGNCLN FISFGYAAQS LLAALGSIQF VSNIAFAYVV LNKMVTVKVL VATAFIVLGN
VFLVAFGNHQ SPVFTPEQLA EKYSNVTFLV YCGILILIVA VNHFLYRKGE VLLSTPGQEI
SSYWKMLLPF SYAVVSGAIG SCSVLFAKSL SNLLRLAMSS SYQLHSWFTY SMLLLFLSTA
GFWMTRLNEG LSLYDAILIV PMFQIAWTFF SICTGFIYFQ EFQVFDALRT TMFISGMLCV
FIGISLLAPD DTRGNESKDN TSSLDSIVSS DVPSEEDRLI SQSSEDGHSK DTRVVVQGMY
MKATDLFAKT KTACLAALGF GEDSINASAI LVMPMVSSKI TGFRGNGLER AKILSMRGSG
WSKLAMEEEG TRMLEKTSHH HHPSKA
//
