ID A0A0D3DHY2_BRAOL Unreviewed; 1083 AA.
AC A0A0D3DHY2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo7g117800.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo7g117800.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo7g117800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A0D3DHY2; -.
DR STRING; 109376.A0A0D3DHY2; -.
DR EnsemblPlants; Bo7g117800.1; Bo7g117800.1; Bo7g117800.
DR Gramene; Bo7g117800.1; Bo7g117800.1; Bo7g117800.
DR HOGENOM; CLU_001561_0_3_1; -.
DR OMA; SHENQHR; -.
DR Proteomes; UP000032141; Chromosome C7.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF600; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 838..975
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 1083 AA; 122297 MW; BB0F25F1BE640CCF CRC64;
MPGIGKTTLA KAVFHQISGG YEASCFIKHF DRAFHEKGLH CLLEEHFGKI LKELPRVCSS
ITRPSLPGDK ISKKRTLVVL DDVQDPLGAL SFLGRFHWFG PGSLIIITSR DKQVFRLCQM
NHVYEVQGLS ENEALQLFSQ CAFGKSIREQ NLLELSMEVI DYANGNPFAL SFYGRELKGK
KVSEMETTFL KLKLPTPYKI HDLFNSSYKT LNDNEKNIFL DIACFFVGED VDYVMPLLEG
CGFFPHVGID ILVEKCLVTI SEKRVLMHRI IQDFGREIIN GESEQMERRS RLWEPWTIKF
LLEANGHPRA TCKRVLGTED IEGIFLDTSN LLFDVKHTAF DNMLNLRFLK IYCSSHENQH
RLGLPRGLES LPYELRLLHW ENYPLEYLPQ DYEPCHLVEL NMSYSHLQKL WGGTKNLEML
KVCRLCHSQQ LTEIDDLCKA RNIEIIDLQG CTKLHRFPPT GQLQHLRVVD LSGCTEIRSF
PDVSPNIEEL HLQGTGIREL PISLVAHVVS SNQNLDKLVL LNMKDCSNLQ SLPQLVDLES
LEVLDLSGCS ELKSIQGFPR NLKRLYIVGT AVKELPPLPW SIELLNAHGC VSLISIPFGF
EKLPRYYTFS NCVALSAQVV SEFVVNSLTN VERMAREYQP ELNKSLAFSL TVPSASSKQF
TCDLQPGSSV MIQLGSWRST LGFAIIVELS FSEDYHEASD FGISCVCRWK DKGFISHRLE
KSFPIWTPGE GVPRDHVFVF CDLNMHPSNC EGNDPYILAD LVVFEFFAVN KEKKPLNESC
TVTKCGVRVI TDANGGASCN MSQPFPSLGY LQESFDSEME EVLRVIFDIL DKNDRNLVLY
IACLFNDEKA DFLTPIIASI DLGISSRLEF LANQSLIHIS PYGIVVRHGL LEKIGREIVV
LSKNYASSSR CLDELVEIMN CNREFQKVVT IFDNVVPSDV GRLADLANID GVNSRKWDNE
AKMLDKTGCD VLEEINHTTS NDSGDVIGVQ DHVTDMGYWS GSESEEVKKT VGISISLEKG
EKINASMVAM PVEPPMIRSE ARSPTFRDRI PFAELYTGEI PAAFLQGLHN IRSVLQSQKS
IRL
//
