ID   A0A0D3DIB7_BRAOL        Unreviewed;       972 AA.
AC   A0A0D3DIB7;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Cytochrome P450 {ECO:0008006|Google:ProtNLM};
OS   Brassica oleracea var. oleracea.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo7g119150.1, ECO:0000313|Proteomes:UP000032141};
RN   [1] {ECO:0000313|EnsemblPlants:Bo7g119150.1, ECO:0000313|Proteomes:UP000032141}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX   PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA   Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA   Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA   Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA   Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA   Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA   Chalhoub B., Sharpe A.G.;
RT   "Transcriptome and methylome profiling reveals relics of genome dominance
RT   in the mesopolyploid Brassica oleracea.";
RL   Genome Biol. 15:R77-R77(2014).
RN   [2] {ECO:0000313|EnsemblPlants:Bo7g119150.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (MAR-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|ARBA:ARBA00001971};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|ARBA:ARBA00010617}.
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DR   AlphaFoldDB; A0A0D3DIB7; -.
DR   STRING; 109376.A0A0D3DIB7; -.
DR   EnsemblPlants; Bo7g119150.1; Bo7g119150.1; Bo7g119150.
DR   Gramene; Bo7g119150.1; Bo7g119150.1; Bo7g119150.
DR   eggNOG; KOG0157; Eukaryota.
DR   HOGENOM; CLU_305322_0_0_1; -.
DR   OMA; DISWKAK; -.
DR   Proteomes; UP000032141; Chromosome C7.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   CDD; cd11064; CYP86A; 2.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 2.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR24296:SF96; ALKANE HYDROXYLASE MAH1-LIKE; 1.
DR   PANTHER; PTHR24296; CYTOCHROME P450; 1.
DR   Pfam; PF00067; p450; 2.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 2.
DR   PROSITE; PS00086; CYTOCHROME_P450; 2.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004}; Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   972 AA;  111207 MW;  D9F64A862582EE48 CRC64;
     MASISLLEAS IAILCFLILF YLLFKKPHDR FPRNWPVVGM LHRLLVSLHQ LYDYGVEILE
     ISDLTFLFKG PRFFGMDMLF TVDPANIHHI MSSNFSNYIK GSDFQDVFDV FGDGIITTDS
     ELWKNLRKSY QAMVHHQEFQ RFSMSTMISK LKDGLVPLLN HFAEEGTTVD LQDLFGRLTF
     DTILILITGS DPRSLSIEMH EDELAKALDD VGEGVLYRHV KPRFMWKLQN WMGLGQEKKM
     SQANATFDRV CSKYISAKRE EIIRSQGVLN GEGEDLLTSF MKLDTAKYKL LKPSDDKFLR
     DTILAFILAG RDTTASALSW FFWLLSENPI VVAKIRQEII DNDLPRTTGN GQENLDKLVY
     LQAALFEAMR LYPPVSFGRK SSVESDVLPS GSMKAVWGED ALQFKPERWI TENGGLKHEP
     SSKFLAFNSG PRTCLGKHLA ITQMKTVVVE ILQNYEVKVI KGQKIEPVLG FILAMKHGLK
     KPFSYLPFQK TLKSYPWNWP VLGMLPGVLV RLHRIYDCSV EVLENSNLTF QFKGPWFSGM
     DILVTVVPAN IHYILSSNFS NYIKGPEFQE IFEAYGDGII NSDSELWRNL RKSSQVIFSH
     QKYQSFSKST TRSKLKDGLL PLLSHFADEE MVVDLQDVFQ RFMFDTTFIF ITGSDPRSLS
     IEMPEVEFAK ALDDVGEAIV YRHITPRFLW KLQKWIGIGR EKTMMKANAV LDRVCAKYIS
     AKREEIRSQE NADEESEDLL TSHIKLDASK YELLNPEDDK FLRDFTVGFM VAGRDSTACT
     LTWFFWILSE NPNVLSKILQ EINENVPITR SDQDKSSYLN KLVYLHAALS ESMRLYPPIP
     FERKSPIKPD VLPSGHKVKS NINIMIFLYA MGRMKDVWGE DAREFKPERW ISETGGLRHE
     PSYKFLSFNA GPRTCLGKNL AMDLMKTVIV EILQAYEINV VSGQKIEAKP GLILHMKHGL
     KVTIAKKCCS LE
//