ID A0A0D3DP05_BRAOL Unreviewed; 1185 AA.
AC A0A0D3DP05;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=106312626 {ECO:0000313|EnsemblPlants:Bo8g059730.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo8g059730.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo8g059730.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo8g059730.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR RefSeq; XP_013605666.1; XM_013750212.1.
DR AlphaFoldDB; A0A0D3DP05; -.
DR STRING; 109376.A0A0D3DP05; -.
DR EnsemblPlants; Bo8g059730.1; Bo8g059730.1; Bo8g059730.
DR GeneID; 106312626; -.
DR Gramene; Bo8g059730.1; Bo8g059730.1; Bo8g059730.
DR KEGG; boe:106312626; -.
DR eggNOG; KOG0351; Eukaryota.
DR HOGENOM; CLU_001103_0_1_1; -.
DR OMA; HLQIMKD; -.
DR OrthoDB; 1114285at2759; -.
DR Proteomes; UP000032141; Chromosome C8.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF135; DNA HELICASE; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141}.
FT DOMAIN 465..640
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 665..810
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 680..721
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 1011..1093
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1094..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1100..1116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1185 AA; 132705 MW; F926D79E22D8C462 CRC64;
MINSNQVSRS HLPEVQKPKV PQTNWSEHAK AFEDPSSRTK HLSSGFLYAL ESQKPRKSRD
MAARSIAFPS VNAHTLAHPQ IAKAWSALSS LSLNKTYLRP GITPPVDDGG TNGSYSARER
STVKVTCSTD GSFYSNNQQN QSQMGVPGTG RNFHSFPPPV PGDGKIFAEK FPRINDEARE
PETCSAHLNG VEKPFRSSAF AAEQLGSGEA CLDEIDDDIL QNIDVDQIMM EHYQSTSTPP
PSVSSLPSRT PPVDRSASRR EEECCLPPEL CSNCSHGIKL GLCPEASTHL EQMKNMLIAI
SNELLDDDTD LSPDRIQELR QERLLLKKQI QQLEDHTRDK EKHKSQFLSS TATRASQCET
PKSTNLRFDH PQTDSQTHFN EQGRYASDSW NMPKDSSLSV DRYGLSSAPV EREQYVPRII
EVTYTEGSND QKWSSRDFPW TRKLEVSNKK VFGNHSFRPN QREIINATMS GSDVFVLMPT
GGGKSLTYQL PALICQGITL VISPLVSLIQ DQIMNLLQAN IPAASLSAGM EWSEQLKIFQ
ELSSEHSKYK LLYVTPEKVA QSDSLLRHLD NLNSCGLLAR FVIDEAHCVS QWGHDFRPDY
QSLGILKQKF PNIPVLALTA TATASVKEDV VQALGLVNCV VFRQSFNRPN LLYSVVPKTK
KCLEDIDKFI KENHFDECGI IYCLSRNDCE KVAQKLQEFG HKAAFYHGSI EPTQRALVQK
QWSKDEVNII CATVAFGMGI NKPDVRFVIH HSLPKSIEGY HQECGRAGRD GQRASCVLYY
GYGDYIRVKH MISQVGVDQN PMAIGYNRVA SSGRLLETNT ENLLRMVRYC ENEVDCRRFL
QLVHFGEKFD STNCKRTCDN CSSSQSLIDK DVTLITRQLV ELVKQTGERF SSSHILEVYR
GSLNQMVKKH RHETLQFHGA GKHLTKLEVS RILHYLVTED ILVEDVRKSD MYGSVSSLLK
VNKSKAASLF SGSQTIMMRF PSSVKVLKPC KAAPTPAKAP LVSADAPPED VNLSAIMYTA
LRKLRTLLVK EAPDGVMAYH IFGNATLQQM SKKIPRTKEE LLEINGLGKA KVLKYGERLL
ETIESTVNEY YGTSKKEESM ISPDSGKRRR DENISPNVTE EDDDFAESSS QSCKKTVRSK
SSEVLHGECV DGGGVGMVME KLDFDFDFED EDGSEIRPEG RVLPW
//
