ID A0A0D3DRD2_BRAOL Unreviewed; 1376 AA.
AC A0A0D3DRD2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Lysine-specific demethylase REF6 {ECO:0008006|Google:ProtNLM};
GN Name=106311772 {ECO:0000313|EnsemblPlants:Bo8g076910.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo8g076910.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo8g076910.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo8g076910.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
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DR RefSeq; XP_013604508.1; XM_013749054.1.
DR SMR; A0A0D3DRD2; -.
DR STRING; 109376.A0A0D3DRD2; -.
DR EnsemblPlants; Bo8g076910.1; Bo8g076910.1; Bo8g076910.
DR GeneID; 106311772; -.
DR Gramene; Bo8g076910.1; Bo8g076910.1; Bo8g076910.
DR eggNOG; KOG1246; Eukaryota.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_001687_1_0_1; -.
DR OMA; MRFREPS; -.
DR OrthoDB; 460721at2759; -.
DR Proteomes; UP000032141; Chromosome C8.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblPlants.
DR GO; GO:0071558; F:histone H3K27me2/H3K27me3 demethylase activity; IEA:EnsemblPlants.
DR GO; GO:0043621; F:protein self-association; IEA:EnsemblPlants.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:EnsemblPlants.
DR GO; GO:0046345; P:abscisic acid catabolic process; IEA:EnsemblPlants.
DR GO; GO:0040029; P:epigenetic regulation of gene expression; IEA:EnsemblPlants.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; IEA:EnsemblPlants.
DR GO; GO:0010286; P:heat acclimation; IEA:EnsemblPlants.
DR GO; GO:0048366; P:leaf development; IEA:EnsemblPlants.
DR GO; GO:0035067; P:negative regulation of histone acetylation; IEA:EnsemblPlants.
DR GO; GO:1902465; P:negative regulation of histone H3-K27 trimethylation; IEA:EnsemblPlants.
DR GO; GO:0010628; P:positive regulation of gene expression; IEA:EnsemblPlants.
DR GO; GO:1901333; P:positive regulation of lateral root development; IEA:EnsemblPlants.
DR GO; GO:0051260; P:protein homooligomerization; IEA:EnsemblPlants.
DR GO; GO:0097355; P:protein localization to heterochromatin; IEA:EnsemblPlants.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:EnsemblPlants.
DR GO; GO:0010104; P:regulation of ethylene-activated signaling pathway; IEA:EnsemblPlants.
DR GO; GO:2000028; P:regulation of photoperiodism, flowering; IEA:EnsemblPlants.
DR GO; GO:0048838; P:release of seed from dormancy; IEA:EnsemblPlants.
DR GO; GO:0009737; P:response to abscisic acid; IEA:EnsemblPlants.
DR GO; GO:0009741; P:response to brassinosteroid; IEA:EnsemblPlants.
DR GO; GO:1904629; P:response to diterpene; IEA:EnsemblPlants.
DR GO; GO:0009612; P:response to mechanical stimulus; IEA:EnsemblPlants.
DR GO; GO:0009627; P:systemic acquired resistance; IEA:EnsemblPlants.
DR GO; GO:0009826; P:unidimensional cell growth; IEA:EnsemblPlants.
DR GO; GO:0010228; P:vegetative to reproductive phase transition of meristem; IEA:EnsemblPlants.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 3.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR003349; JmjN.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF38; LYSINE-SPECIFIC DEMETHYLASE REF6; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF02375; JmjN; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00545; JmjN; 1.
DR SMART; SM00355; ZnF_C2H2; 4.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51183; JMJN; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000032141};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 20..61
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
FT DOMAIN 205..371
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
FT DOMAIN 1282..1311
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1312..1341
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1342..1373
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 76..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 504..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 604..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 911..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1067..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..518
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..939
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 940..973
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..994
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1205..1231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1376 AA; 153430 MW; 105B7DAEDB741EE0 CRC64;
MAVSEQSQDV FPWLKSLPVA PEFKPTLAEF QDPMAYICKI EEEASRYGIC KIVPPVPPSS
KKTAINNLNR SLAARARARA RDGNGNGGKS DYDDGPTFTT RQQQIGFCPR RQRPVQRPVW
QSGERYTFDE FEFKAKNFEK SYLKKCGKKG SVSPLEVETL YWRASVDKPF SVEYANDMPG
SAFVPLSLAA ARRRESGGDC GTVGETAWNM RAMARAEGSL LKFMKEEIPG VTSPMVYIAM
MFSWFAWHVE DHDLHSLNYL HMGAAKTWYG VPKDAAMAFE EVVRVHGYGE ELNPLVTFST
LGEKTTVMSP EVFVRAGIPC CRLVQNPGDF VITFPGAYHS GFSHGFNFGE ASNIATPQWL
RMAKDAAIRR ASINYPPMVS HLQLLYDYAL ALGSRVPDSI HNKPRSSRLK DKKKSEGEKL
TNELFVQNVI HNNELLHSLG KGSPIALLPQ SSSDVSVCSD VRIGSHLGAN QGQTTLLIKS
EDLSSDSVMA SLSNGVKEKF TSLCERNRAD ETQGTSTDGE KRKNNGAVGL SDQRLFSCVT
CGVLSFDCVA IIQPKEAAAR YLMSADCSSL NDWTVASGSA NLGQDVVMPP SGKQDVGDLY
NAPVQTPYHS TTKTVDQRTS SSSLTKENGA LGLLASAYGD SSDSEEEDHK GLDNPVSDEV
EASSFVTDGN DEAGNGLSSA LNSQGLTCEK GKEVDVSHAN LSKGGNTSSV EITLPFIPRS
DDDFSRLHVF CLEHAAEVEQ RLHPIGGINI MLLCHPDYPR IEAEGKVVAK ELGVNHEWND
TEFKNVTRED EETIQAALAN VEAKAGNSDW AVKLGINLSH SAILSRSPLY SKQMPYNSVI
YNVFGRTSPA TPQVSGIRSS RQRKYVAGKW CGKVWMSHQV HPFLLEEDLE GEETERSHLR
AALDEDVTVH GNDSRDATTM FGRKYSRKRK ARGKAAPRKK LTSFKREAGV SDDTTSEDHS
YKQQWRAYGD EEESYFETGN EVSGDSSNQM SDQQQLKVVE SDDDEVSERS LGQEYAVRRE
YASSESSMEN GFQVYREDQP MYGDDDMYRH PRGIPRNKRT KVFRDLVSYD SEDQQRERVF
TSDAQTSRMG DEYDSEENSL EEQDFCSSGK RQTRSIAKRK VKTKIVQSLG DTGGRTLLQS
GSRKKMKELD SYMEGPSTRL RVRTPKPSRG SSATKPKKTG KKGRNVSFSE VASEEEVEEN
EEESEEASTR IRVRTLKPPR RSLETKPKKT GKKGSNVSLS GVASEEEVEE NEQEECLPYQ
CDMEGCTMSF SSEKQLSLHK RNICPVKGCG KTFFSHKYLV QHQRVHSDDR PLKCPWKGCK
MTFKWAWSRT EHIRVHTGER PYICAEPGCS QTFRFVSDFS RHKRKTGHSA KKIKKK
//
