ID A0A0D3E3D5_BRAOL Unreviewed; 3891 AA.
AC A0A0D3E3D5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:Bo9g026320.1};
OS Brassica oleracea var. oleracea.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=109376 {ECO:0000313|EnsemblPlants:Bo9g026320.1, ECO:0000313|Proteomes:UP000032141};
RN [1] {ECO:0000313|EnsemblPlants:Bo9g026320.1, ECO:0000313|Proteomes:UP000032141}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. TO1000 {ECO:0000313|Proteomes:UP000032141};
RX PubMed=24916971; DOI=10.1186/gb-2014-15-6-r77;
RA Parkin I.A., Koh C., Tang H., Robinson S.J., Kagale S., Clarke W.E.,
RA Town C.D., Nixon J., Krishnakumar V., Bidwell S.L., Denoeud F., Belcram H.,
RA Links M.G., Just J., Clarke C., Bender T., Huebert T., Mason A.S.,
RA Pires J.C., Barker G., Moore J., Walley P.G., Manoli S., Batley J.,
RA Edwards D., Nelson M.N., Wang X., Paterson A.H., King G., Bancroft I.,
RA Chalhoub B., Sharpe A.G.;
RT "Transcriptome and methylome profiling reveals relics of genome dominance
RT in the mesopolyploid Brassica oleracea.";
RL Genome Biol. 15:R77-R77(2014).
RN [2] {ECO:0000313|EnsemblPlants:Bo9g026320.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR STRING; 109376.A0A0D3E3D5; -.
DR EnsemblPlants; Bo9g026320.1; Bo9g026320.1; Bo9g026320.
DR Gramene; Bo9g026320.1; Bo9g026320.1; Bo9g026320.
DR eggNOG; KOG0889; Eukaryota.
DR HOGENOM; CLU_000129_1_0_1; -.
DR OMA; CLDLYGQ; -.
DR Proteomes; UP000032141; Chromosome C9.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd05163; PIKK_TRRAP; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR046807; Tra1_central.
DR InterPro; IPR046805; Tra1_ring.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF1; TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF20175; Tra1_central; 2.
DR Pfam; PF20206; Tra1_ring; 1.
DR SMART; SM01343; FATC; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032141}.
FT DOMAIN 2691..3234
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 3519..3842
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 3859..3891
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
FT REGION 2033..2073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2087..2108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2320..2341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3258..3321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2041..2055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2087..2103
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3270..3321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3891 AA; 439897 MW; 1829ACFD5CA5909C CRC64;
MSPIQNFEQH SRRLVDPDLP IQTRLEMVVE VRDSLEIAHT AEYLNFLKCY FPAFSVILLQ
ITKPQLVDNP EHKLRNIVVE ILNRLPHSEV LRPFVQDLLK VAMQVLTTDN EENGLICIRI
IFDLLRNFRP TLENEVQPFL DFVCKIYQVF RFTVSHFFDN VKMEEVKPVE TSASSDQSLT
PVAPVGNGQL NPSTRSFKII TESPLVVMFL FQLYSRLVQT NIPHLLPLMV AAISVPGPEN
VPSHLKPQFI ELKGAQVKTV SFLTYLLKSC AEYIRPHEES ICKSIVNLLV TCSDSASIRK
ELLVSLKHVL GTDFKRGLFP LIDTLLDERV LVGTGRACFE SLRPLAYSLL AEIVHHVRGD
LSLSQVIIDE ELLIVFNVDL DILWIHHKRN TPLQYALSRI IYLFSRNMHD STLSLSIHTT
CARLMLNLVE PIFEKGVDQQ SMNEARILLG RILDAFVGKF STFKRTIPQL LEEGEVGKDR
VTLRAKLELP VQAVLNLQVP VEHSKEVNDC KNLIKTLVMG MKTIIWSITH AHLPRPQGLN
PQALASQASA PQGFKGMRED EVWKASGVLK SGVHCLALFK EKDEEKEMLS LFSQILAIME
PRDLMDMFSL CMPELFECMI NNNQLVQIFA ALLQAPKVYK SFADVLINLL VSSKLDVLKN
PDSDATKLVL HLFRCIFGAV TKAPLDFERI LQHHVPVIME VCMKNATEVE KPLGYMQLLR
TVFRGLAGCK YELLLRDLIP MLLPCLNILL TMLEGPAGED MKDLLLELCL TLPARLSSLL
PYLPRLMKPL VFCLRGSDEL VSLGLRTLEF WVDSLNPDFL EPSMANVMSE VILALWSHLR
PVPYPWGGKA LQILGKLGGR NRRFLKEPLT LECKDNPEHG LRVVLTFEPS TPFLVPLDKF
INLAVGAVIH RNQGIDIYYR KQALKFLRVC LLSQLNLPGC VTDVGQTPRQ LSTLLRSSVD
SSWHRSESVE VKADLGVKTK TQLMAEKSIF KTLLITILAA SSDPDLRDSD DDFVVNICRH
FAIILHIDYT STNASTSTGS LGAVISASSR TRGNRSSNLK QLDPLIFLDA LVDVLADENR
LHAKAALNAL NVFSETLLFL ARVKHADVLM ARGGHNASMI VSSPSTNPVY SPHPSVRIPV
FEQLLPRLLH GCYGSTWQAQ MGGVMGLGAL VGKVNVETLC HFQVKIVRGL VYVLKRLPVY
ASKEQEETSQ VLMQILRVVN NVDEANSEAR RKSFQDVVEY LATELFNPNA SIPVRKNVQN
CLALLASRTG SEVTELLEPL YQVLLQPLIM RPLRSKTVDQ QGGTVAALNF CLALRPPLLK
VTPELVNFLQ EALQIAEADE TVWTVKLMNP KVLTSLNRLR TACIELLCTT MAWTDFRTQA
HNELRAKIIS MFFKSLTCRA PEIVAVAKEG LRQVINQQRM PKELLQSSLR PILVNLAHTK
NLSMPLLQGL ARLLELLSNW FNVTLGGKLL EHLKKWLEPE KLAQSQKSWK AGEEPKIAAA
IIELFHLLPQ AASKFLDELV TLTIDLEAAL PPGQVYSEIN SPYRLPLTKF LNRYASLAVD
YFLSRLSEPK YFRRFMYIIR SDAGQPLREE LAKSPQKILS YAFPEMLPKP DATMSMEAST
LPAKSCGDEN LVSVKSESSN TAQTKANVAS DAYFQGLYLI KTMVKLIPSW LQSNRSVFDT
LVLIWKSPSR ISRLQNEQEL NLVQVKESKW LVKCFLNYLR HEKSEVNVLF DILSIFLFHS
RIDYTFLKEF YIIEVAEGYP PNIKRALLLH FLDIFHSKQL GHDHLVQAMQ MLILPMLSHA
FQNGQTWEVI DPDIVKTIVE RLLDPPEEVS AEYDEPLRIE LLQLATLLLK YLQSDLVHHR
KELIKFGWNH LKREDSASKQ WAFVNVCHFL DAYQAPEKII LQISWYYDRI LFPESETCQP
ENKMLVKQAL DILMPALPKR LPLGDSRMPI WIRYTKKILV EEGHSIPNLI HIFLLVVRHS
DLFYSCRAQF VPQMVNSLSR LGLPYNTTAE NRRLAIELAG LVVSWERQRQ NEMKTVTDTD
GTSHATDELH LSSGADSKRS TDGSATSEDP SKRVKIEPGL QSICVMSPGG ASSIPNVETP
GSATQPDEEF KPNAAMEEMI INFLIRVALV IEPKDRETNT MYKQALDLLS EALEVWPNAN
VKFNYLEKLL SSMPPSQSDP STALAQGLDV MNKVLEKQPH LFIRNNINQI SQILEPCFKH
KMLDAGKSLC SLLKMVFTAF PMDAASTPPD IKLLYQKVNE LINKHVSAVT APQASGDDTS
FGSISFVLLV IKTLAKVHKN FVDSYVVVRI LQRLARDLGS AVGSHPRQGP RADSDSAVTS
SRQSADVGSV ICNIKSVLEL IDETVMLIPD CKRSVTQILN TLLSEKGTDA SVLLCILDML
KRWVEDDFSK TSASGMSGSF LTQKDVVAFL SKLSYIDKQH FSSDALEEWD QKYLQLLYGL
CADSTKYPLA LRQEVSLKVE RHFMLGLRAR DPEMRRKFFL LYHESLGKNL FSRLQYIIQI
QDWEALSDVF WLKQGLDLLL AILVEDKPIS LAPNSARVIP LLPSDNPGIQ HQPLATLEGP
DEVTSMFDNI VMKHAQFLSA ASKLQVADVV IPLRELAHTD ANVAYHLWVL VFPIVWVTLL
KEEQVALAKP MISLLSKDYH KKQQGHRPNV VQALLEGLQL SHPQPRMPSE LIKYIGKTYN
AWHLALALLE SHVMLFMNDS KCAESLAELY RLLNEEDMRF GLWKKRSITA ETRAGLSLVQ
HGFWQHSQSL FYQAMVKATQ GTYNNTVPKA EMCLWEEQWL HCAAQLGQWD ALVDFGKSIE
NYEILLDGLW KLPDWAYLKD HVIPKAQVEE TPKLRLVQAY FALHDRNSNG VGDAENIVGK
GVDLALEQWW QLPEMSVHAR VPLLQQFQQL VEVQESARIH VDIANGNKVS GNAAVGALGN
RYADLKDILE TWRLRTPNEW DNMTVWYDML QWRNEMYNVV IEAFKDFAAS NSPLHHLGFR
DKAWNVNKLA RIARKQGLYD VCVQILEKMY GHSTMEVQEA FVKIREQAKA YLEMKGELAS
GLNLINSTNL EYFPDKIKAE IVRLKGDFHL KLNDTEGANI AYSNAITLFK NLPKGWISWG
NYCDMAYQET QDEIWLEYAV NCFLQGIKFG VSNSRSHIAR VLYLLSFDTA NEPVGRVFDK
HLEQVPHWVW LSWIPQLLLS LQRTEAPHCK LVLLKIATVF PQALYYWLRT YLLERRDAVN
KSELGRMVLA QRMQQNASGV AGHGGGNLPS ETHQGAQISG AGGTHNSGNP HGQESERSTA
ENNAHPGNDQ SMHQSNSTNS ENIARQNGAS LAISAAGAFD AAKDIMEALR SKHNNLASEL
EVLLTEIGSR FVTLPEERLL AVVNALLHRC YKYPTATTAE VPQPLKKELS GVCRACFSAD
AVTKHVEFVK EYKQEFENHL DPESTSTFPA TLAELTNRLK NWKNILQSNV EDRFPAVLRL
EDESRVLRDF NVVDVEIPGQ YFSDQEVAPD HTVKLDRVGA DVPIVRRHGS SFRRLTLIGS
DGSQKHFIVQ TSLTPNARSD ERILQLFRVM NQMFDKHKES RRRHIGIYTP IIIPVWSQVR
MVEDDLMYNT FLEVYENHCA RNDREADLPI SHFKEQLNQA ISGQVSAEAI GDLRLQAYSD
ITKTLVNDSI FSQYMYKTLM SGSHMWAFKK QFAVQLAVSS FMSFMLQIGG RSPNKVLFAK
NTGKMFQTDF HPAYDANGMI EFNEPVPFRL TRNMQAFFSQ FGVEGLLMSS MCSAAQAVIS
SKQNDHLRYQ LAMFFRDELL SWFGRRPLGM PIPPAGGIAT LNSAELKEKV NSNVNDVIGR
IRGIAPQYFS EEDENIVEPP QSVQRGVNEL VEAALSPRNL CMMDPTWHPW F
//
