ID A0A0D3F8S0_9ORYZ Unreviewed; 706 AA.
AC A0A0D3F8S0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=mRNA m(6)A methyltransferase {ECO:0000256|ARBA:ARBA00012160};
DE EC=2.1.1.348 {ECO:0000256|ARBA:ARBA00012160};
OS Oryza barthii.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=65489 {ECO:0000313|EnsemblPlants:OBART02G27500.1};
RN [1] {ECO:0000313|EnsemblPlants:OBART02G27500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 105608 {ECO:0000313|EnsemblPlants:OBART02G27500.1};
RX DOI=10.1007/s12284-009-9025-z;
RA Rounsley S., Marri P.R., Yu Y., He R., Sisneros N., Goicoechea J.L.,
RA Lee S.J., Angelova A., Kudrna D., Luo M., Affourtit J., Desany B.,
RA Knight J., Niazi F., Egholm M., Wing R.A.;
RT "De novo next generation sequencing of plant genomes.";
RL Rice 2:35-43(2009).
RN [2] {ECO:0000313|EnsemblPlants:OBART02G27500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-
CC methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:55584, Rhea:RHEA-COMP:12414, Rhea:RHEA-COMP:12417,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.348;
CC Evidence={ECO:0000256|ARBA:ARBA00036277};
CC -!- SIMILARITY: Belongs to the MT-A70-like family. {ECO:0000256|PROSITE-
CC ProRule:PRU00489}.
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DR AlphaFoldDB; A0A0D3F8S0; -.
DR SMR; A0A0D3F8S0; -.
DR STRING; 65489.A0A0D3F8S0; -.
DR PaxDb; 65489-OBART02G27500-1; -.
DR EnsemblPlants; OBART02G27500.1; OBART02G27500.1; OBART02G27500.
DR Gramene; OBART02G27500.1; OBART02G27500.1; OBART02G27500.
DR eggNOG; KOG2098; Eukaryota.
DR HOGENOM; CLU_018702_3_0_1; -.
DR Proteomes; UP000026960; Chromosome 2.
DR GO; GO:0016607; C:nuclear speck; IEA:EnsemblPlants.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IEA:EnsemblPlants.
DR GO; GO:0080009; P:mRNA methylation; IEA:EnsemblPlants.
DR InterPro; IPR007757; MT-A70-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12829; N6-ADENOSINE-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12829:SF2; N6-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT; 1.
DR Pfam; PF05063; MT-A70; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51143; MT_A70; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000026960};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 64..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 77803 MW; 91BDDF2AAEABA405 CRC64;
MEAQADAGGD DLAAMREQCR SLEEAIGFRR ETQMGLVASL QRLVPDLVPS LDRSLRIIAA
FNDRPFVPTP NPDGGHGKSP AALKPHHRRA LPDPARSTRR KTSPGSSPAS VAAAPGGLDA
VRTMVAVCLL ELVPFAEIDA AALARRLQAE SSSASEAERT ALADLAAELG GSAASAVVLA
LRRIAEDTGG VQIEEAMIGG KSMTMVWAID RNKLLKELPE SATLPLLQPP PAPQMPPSET
DAGSAMIPRT PQQQQPQPDM WPHSMPPIFP RPRGMTMQGM QRVPGVPPGL MPLQRPFMGP
AGVITMGGGV GPSPNQQKQK SEEDELKDLE LLLNKKTYRE KQNTKTGEEL LDLIHRPTAK
ETAVAAKFKT KGGSQLKEYC TNLTKEDCRR QSGSFVACDK VHFRRIIAPH TDTNLGDCSF
LDTCRHTKTC KYVHYELDQT PDIPPMMAGA LAPPRQIRLQ RAEYCSEVEL GEAQWINCDI
RNFRMDILGQ FGVIMADPPW DIHMELPYGT MADDEMRTLN VPALQTDGLI FLWVTGRAME
LGRECLELWG YKRVEEIIWV KTNQLQRIIR TGRTGHWLNH SKEHCLVGIK GNPLVNRNID
TDVIVAEVRE TSRKPDEMYP MLERISPRTR KLELFARMHN AHAGWLSLGN QLNGVRLVDE
GLRARYKAAY PDSEVQPPSP PRASAPIDGD QGTSQKPTVS DGERPA
//
