ID A0A0D3HGI8_9ORYZ Unreviewed; 958 AA.
AC A0A0D3HGI8;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Peptidase metallopeptidase domain-containing protein {ECO:0000259|SMART:SM00235};
OS Oryza barthii.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=65489 {ECO:0000313|EnsemblPlants:OBART10G18270.1};
RN [1] {ECO:0000313|EnsemblPlants:OBART10G18270.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 105608 {ECO:0000313|EnsemblPlants:OBART10G18270.1};
RX DOI=10.1007/s12284-009-9025-z;
RA Rounsley S., Marri P.R., Yu Y., He R., Sisneros N., Goicoechea J.L.,
RA Lee S.J., Angelova A., Kudrna D., Luo M., Affourtit J., Desany B.,
RA Knight J., Niazi F., Egholm M., Wing R.A.;
RT "De novo next generation sequencing of plant genomes.";
RL Rice 2:35-43(2009).
RN [2] {ECO:0000313|EnsemblPlants:OBART10G18270.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|PIRSR:PIRSR621190-2};
CC Note=Can bind about 5 Ca(2+) ions per subunit.
CC {ECO:0000256|PIRSR:PIRSR621190-2};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|PIRSR:PIRSR621190-2};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000256|PIRSR:PIRSR621190-
CC 2};
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DR AlphaFoldDB; A0A0D3HGI8; -.
DR STRING; 65489.A0A0D3HGI8; -.
DR MEROPS; M10.A01; -.
DR PaxDb; 65489-OBART10G18270-1; -.
DR EnsemblPlants; OBART10G18270.1; OBART10G18270.1; OBART10G18270.
DR Gramene; OBART10G18270.1; OBART10G18270.1; OBART10G18270.
DR eggNOG; KOG1565; Eukaryota.
DR HOGENOM; CLU_321706_0_0_1; -.
DR Proteomes; UP000026960; Chromosome 10.
DR GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04278; ZnMc_MMP; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 4.
DR InterPro; IPR033739; M10A_MMP.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001818; Pept_M10_metallopeptidase.
DR InterPro; IPR021190; Pept_M10A.
DR InterPro; IPR006026; Peptidase_Metallo.
DR PANTHER; PTHR10201; MATRIX METALLOPROTEINASE; 1.
DR PANTHER; PTHR10201:SF249; METALLOENDOPROTEINASE 1-MMP; 1.
DR Pfam; PF00413; Peptidase_M10; 4.
DR PRINTS; PR00138; MATRIXIN.
DR SMART; SM00235; ZnMc; 3.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 4.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|PIRSR:PIRSR621190-2};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR621190-2}; Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000026960};
KW Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PIRSR:PIRSR621190-2}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..958
FT /note="Peptidase metallopeptidase domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002264115"
FT DOMAIN 53..179
FT /note="Peptidase metallopeptidase"
FT /evidence="ECO:0000259|SMART:SM00235"
FT DOMAIN 240..419
FT /note="Peptidase metallopeptidase"
FT /evidence="ECO:0000259|SMART:SM00235"
FT DOMAIN 607..784
FT /note="Peptidase metallopeptidase"
FT /evidence="ECO:0000259|SMART:SM00235"
FT REGION 206..232
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 797..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 375
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-1"
FT BINDING 298
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 320
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 325
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 326
FT /ligand="Ca(2+)"
FT /ligand_id="ChEBI:CHEBI:29108"
FT /ligand_label="3"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 335
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 346
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 374
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 378
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 384
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
FT BINDING 392
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR621190-2"
SQ SEQUENCE 958 AA; 105726 MW; 6ADA03E32D45DC2F CRC64;
MFPRRRGDAA CLLLLAIACI LSCVAVAGAR PMPPPPTLRH HGGVVSRYAF WTGKPRWTRH
GRPMVLTYAV SHTDAVGYLP GDAVLAVFRS AFARWAEVIP SSRDGALLAH SLPAKDGDRD
TAAAAVDLET VATHEIGHAL GLDHSTSESS VMYPYVGTRE RKVRLTVDDV EGIQELYGVN
PSFSFLDYFT PDHDTPRSHV ARLTATQPAL AQTTMTTTLQ PRPEDNNNDS GAGPFTFFPG
KPRWTRPDRV LTYAVSPTAT ADHLSPSAVR AALRSAFARW ADVIPMRFLE AERYDAADIK
VGFYLYTDGR CDGCACIDSD DDDDDGDDCE GVLAHSSMPE KSGQIHLHAA HRWTVNLAAD
TAPLAVDLES VAAHEIGHVL GLDHSSSRSS MMYPFISCRE RKVRLTTDDV HGIQELYGAN
PHFSFGAYFK QDILSRIQQM KKEKKKKARG SSFWQRGLAL TCALVNKDSM IGYISELYSS
IKELDMMNKI NYVYFLDYVG NRTVEKKDPN MHQLRESIRI LTVEIKRWMR FAQIHWVELM
PTLEDLNPCI ARYVTTINTL VLQLTGGTYT YTMFLLCGCG TGSQPTRLRS QDNNGGGGAA
AFTFLRGRPR WNRPDMRLTY AVSPLATADH LPRDAVREAF RSALARWAEV TPLRFAEAAR
YEEADIRVGL YLHASGAGGD GCDGCGHIDD KSSRDGALLA HSLPAKDGRI HMHAARRWTV
DLDRDTAAAA VDLESVATHE IGHVLGLGHS SSKSSVMYRY VRYRERKVDL TEDDVHGVQE
LYGANPHFSF NHIDQNKLAP TTTTTPPLQP RPEDSNDNDN GGAVATSLFT FLPGKPRWTR
PFLTYAVSPA TAVTVGNHVP LNAVRAVFRR AFARWAGVIP VRFVEALRDD DTADIMIGFY
LHTADGKCDA CGCVCKGGGE EALAHAHPRW TVNLAADTAP LAVDLESVAV HTRRRRAR
//
