ID A0A0D3HWJ6_9ORYZ Unreviewed; 737 AA.
AC A0A0D3HWJ6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial {ECO:0008006|Google:ProtNLM};
OS Oryza barthii.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza.
OX NCBI_TaxID=65489 {ECO:0000313|EnsemblPlants:OBART12G18280.1};
RN [1] {ECO:0000313|EnsemblPlants:OBART12G18280.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IRGC 105608 {ECO:0000313|EnsemblPlants:OBART12G18280.1};
RX DOI=10.1007/s12284-009-9025-z;
RA Rounsley S., Marri P.R., Yu Y., He R., Sisneros N., Goicoechea J.L.,
RA Lee S.J., Angelova A., Kudrna D., Luo M., Affourtit J., Desany B.,
RA Knight J., Niazi F., Egholm M., Wing R.A.;
RT "De novo next generation sequencing of plant genomes.";
RL Rice 2:35-43(2009).
RN [2] {ECO:0000313|EnsemblPlants:OBART12G18280.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (MAR-2015) to UniProtKB.
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
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DR AlphaFoldDB; A0A0D3HWJ6; -.
DR EnsemblPlants; OBART12G18280.1; OBART12G18280.1; OBART12G18280.
DR Gramene; OBART12G18280.1; OBART12G18280.1; OBART12G18280.
DR HOGENOM; CLU_000395_3_1_1; -.
DR Proteomes; UP000026960; Chromosome 12.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR045774; MCCA_BT_dom.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR Pfam; PF19331; MCCA_BT; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00866; CPSASE_1; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Reference proteome {ECO:0000313|Proteomes:UP000026960}.
FT DOMAIN 38..485
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 157..355
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 656..732
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
FT REGION 636..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..660
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 80342 MW; 0CDB9A78C94B7F8B CRC64;
MASRLLLLPR RRSRHGGASL LLARLLSSSS SEAGGGGAVE KVLVANRGEI ACRVMRTARR
LGIPTVAVYS DADRGALHVR AADEAVRLGP PPARESYLNA SAIVDAALRT GAKAIHPGYG
FLSESADFAQ LCKAEGLTFI GPPPSAIRDM GDKSASKRIM GAAGVPLVPG YHGAEQDIEL
LKLEANKIGY PVLIKPTHGG GGKGMRIVQR PEDFVDSVLS AQREAAASFG INTLLVEKYI
TQPRHIEVQI FGDQHGNVIH LYERDCSLQR RHQKIIEEAP APNVTAQFRS HIGEAAVSAA
KAVGYYSAGT VEFIVDTLSG EFYFMEMNTR LQVEHPVTEM IVGQDLVEWQ IRIANGECLP
LSQEQVPLNG HAFEARIYAE NVPRGFLPAT GTLHHYRPVP STATVRVETG VEEGDTVSMH
YDPMIAKLVV WGESRNAALV KLKNSLSNFQ IAGLPTNVGF LQELAGHSAF EKGLVDTHFI
ERYQNDLLST STQALSGSHE AEELGAILAA ACICKKDHVS SEVSLHDKKL SMWYAHPPFR
MHHFAKRLME FELDRELGGS SDDLLKLSVT YRSDGTYFVE TEDGSSPGLD VKVDSRGDHD
FRVDVDGLQT DVTLAFYSKD NCNHIHIWHG KHHHHYRQTL RAEQSPDDSS QPSASSEARS
HPKGSVLAPM AGLVVKVLLK DGARVEEGQP VMVMEAMKME HVVKAPCAGY VEGLKATAGQ
QVFDSSVLFT VKENKPN
//
