ID A0A0D3LAU0_9BACT Unreviewed; 633 AA.
AC A0A0D3LAU0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=D770_04720 {ECO:0000313|EMBL:AHM59211.1};
OS Flammeovirgaceae bacterium 311.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Flammeovirgaceae.
OX NCBI_TaxID=1257021 {ECO:0000313|EMBL:AHM59211.1, ECO:0000313|Proteomes:UP000064112};
RN [1] {ECO:0000313|EMBL:AHM59211.1, ECO:0000313|Proteomes:UP000064112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=311 {ECO:0000313|EMBL:AHM59211.1,
RC ECO:0000313|Proteomes:UP000064112};
RA Fang C.;
RT "Complete bacteria genome obtained just from illumina data.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
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DR EMBL; CP004371; AHM59211.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D3LAU0; -.
DR STRING; 1257021.D770_04720; -.
DR REBASE; 106948; Fba311ORF4720P.
DR KEGG; fbt:D770_04720; -.
DR PATRIC; fig|1257021.3.peg.1089; -.
DR OrthoDB; 9814572at2; -.
DR Proteomes; UP000064112; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42933:SF1; SITE-SPECIFIC DNA-METHYLTRANSFERASE (ADENINE-SPECIFIC); 1.
DR PANTHER; PTHR42933; SLR6095 PROTEIN; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000064112};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 303..585
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
SQ SEQUENCE 633 AA; 72459 MW; E2B3B5C8B695ADF4 CRC64;
MAKKEVLTDY WVYELLKEAN INLHPQGSNI KEIDDALKSA SKAGTGNVGF PEYCGVVKDF
VLIIENKADV AQHIRRNEMD VICNEVTSVK NYAVNGALFY GKHLARNTSY KKIIAFGVSG
NAKRHIISPI FIDERGGYKE LEEVETFTLF NTKNIDQYYT INILKEQTTE EKTTEEILKD
AKNLHEDLRN YGSIQDKDKP LIVSGILLAL REMEHKGFSI DSLVGDQTTT DGEKIYEAIE
KNLKRANVSP QVKKDKLLSQ FLVIKDTKAI NEINEYLKKT PLKHYTEFLY ENIYKNIKYI
HSAEDYLGRF YGEFMSYSGG DGQSLGIVLT PKHITELFCE LVELKPTDTV FDPCCGTAGF
LIAAMHDMLQ KTDNPEQQRK IRKNQLHGLE LQPYMFTIAT TNMILRGDGK SNLEQEDFLK
QNPAQLQEKG CTVGMINPPY SMGSKNNTSL YEINFTEHLL NSIVQDGKAI VIVPQSSMTG
KTKEEQAIKA NILKRHTLEG VISLNKNTFY GVGTNPCIAV FTTGVPHYKE KEVKFINFEK
DGFEVQKHRG LVETIEAKDK KQHLLDVWFD RIDTETKFCV KTTIEPEDEW LHSFYYFNDE
TPKVEDFEKT VADYLTFEFS MIMQGREYIF ENE
//
