ID   A0A0D3MDF4_9CIRC        Unreviewed;       310 AA.
AC   A0A0D3MDF4;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Replication-associated protein {ECO:0000256|ARBA:ARBA00014531};
DE   AltName: Full=ATP-dependent helicase Rep {ECO:0000256|ARBA:ARBA00030754};
DE   AltName: Full=RepP {ECO:0000256|ARBA:ARBA00032243};
OS   Bat associated cyclovirus 7.
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes;
OC   Cirlivirales; Circoviridae; Cyclovirus; Cyclovirus liliac.
OX   NCBI_TaxID=1987732 {ECO:0000313|EMBL:AIF76279.1, ECO:0000313|Proteomes:UP000136611};
RN   [1] {ECO:0000313|Proteomes:UP000136611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wu Z., Yang L., Jin Q.;
RT   "Mammalian viruses resident in respiratory and gastrointestinal tracts of
RT   bat species across China mainland.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC         Evidence={ECO:0000256|ARBA:ARBA00001836};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SUBCELLULAR LOCATION: Host nucleus {ECO:0000256|ARBA:ARBA00004147}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the nanoviruses/circoviruses replication-
CC       associated protein family. {ECO:0000256|ARBA:ARBA00008545}.
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DR   EMBL; KJ641740; AIF76279.1; -; Genomic_DNA.
DR   OrthoDB; 9195at10239; -.
DR   Proteomes; UP000136611; Segment.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 3.40.1310.20; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000605; Helicase_SF3_ssDNA/RNA_vir.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003365; Viral_rep_N.
DR   Pfam; PF00910; RNA_helicase; 1.
DR   Pfam; PF02407; Viral_Rep; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Host nucleus {ECO:0000256|ARBA:ARBA00022562}.
FT   DOMAIN          10..95
FT                   /note="Viral replication-associated protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02407"
FT   DOMAIN          167..252
FT                   /note="Helicase superfamily 3 single-stranded DNA/RNA
FT                   virus"
FT                   /evidence="ECO:0000259|Pfam:PF00910"
SQ   SEQUENCE   310 AA;  36413 MW;  70AF6616B6A60E22 CRC64;
     MDLQNARRSR WCFTVNNYTS EHIEQLRKLG STLLTSGYLI FGYENAPTTN TQHLQGYVRL
     NKPKLFRQLQ LLLPPATHIE STKGTERQNY RYCTKSGTFE EFGIQRTQGQ RTDLEQAVHE
     LLHENGTILQ VATNNPTVYV RNWRGLHELR NLLIPVKPRD FRSNIYILYG PTRTGKSRAA
     QKIAGDTSTY YKNRSNWWHG YHQEETVIID DFYGWIKWDE LLKLCDRYPY KVETKGGYEE
     FTSKTIIITS NMPPEKWYKF ENFDPTPLIS DRINAIVETG GTQIKIKTYY EPMKTEDIEL
     INKSFNFIDP
//