ID A0A0D3R3W9_GOSHI Unreviewed; 641 AA.
AC A0A0D3R3W9;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=1-phosphatidylinositol 4-kinase {ECO:0000256|ARBA:ARBA00012169};
DE EC=2.7.1.67 {ECO:0000256|ARBA:ARBA00012169};
GN Name=PI4K2 {ECO:0000313|EMBL:AJR30359.1};
GN Synonyms=LOC107919958 {ECO:0000313|RefSeq:XP_016704899.1};
OS Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX NCBI_TaxID=3635 {ECO:0000313|EMBL:AJR30359.1};
RN [1] {ECO:0000313|EMBL:AJR30359.1}
RP NUCLEOTIDE SEQUENCE.
RA Liu G.-J., Xiao G.-H., Liu N.-J., Liu D., Chen P.-S., Qin Y.-M., Zhu Y.-X.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AJR30359.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=25731673;
RA Liu G.J., Xiao G.H., Liu N.J., Liu D., Chen P.S., Qin Y.M., Zhu Y.X.;
RT "Targeted lipidomics studies reveal that linolenic acid promote cotton
RT fiber elongation by activating phosphatidylinositol and
RT phosphatidylinositol monophosphate biosynthesis.";
RL Mol. Plant 0:0-0(2015).
RN [3] {ECO:0000313|Proteomes:UP000189702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. TM-1 {ECO:0000313|Proteomes:UP000189702};
RX PubMed=25893780; DOI=10.1038/nbt.3208;
RA Li F., Fan G., Lu C., Xiao G., Zou C., Kohel R.J., Ma Z., Shang H., Ma X.,
RA Wu J., Liang X., Huang G., Percy R.G., Liu K., Yang W., Chen W., Du X.,
RA Shi C., Yuan Y., Ye W., Liu X., Zhang X., Liu W., Wei H., Wei S., Huang G.,
RA Zhang X., Zhu S., Zhang H., Sun F., Wang X., Liang J., Wang J., He Q.,
RA Huang L., Wang J., Cui J., Song G., Wang K., Xu X., Yu J.Z., Zhu Y., Yu S.;
RT "Genome sequence of cultivated Upland cotton (Gossypium hirsutum TM-1)
RT provides insights into genome evolution.";
RL Nat. Biotechnol. 33:524-530(2015).
RN [4] {ECO:0000313|RefSeq:XP_016704899.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_016704899.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR EMBL; KP197052; AJR30359.1; -; Genomic_DNA.
DR RefSeq; XP_016704899.1; XM_016849410.1.
DR PaxDb; 3635-A0A0D3R3W9; -.
DR GeneID; 107919958; -.
DR KEGG; ghi:107919958; -.
DR OMA; DCEDDHE; -.
DR OrthoDB; 1699at2759; -.
DR Proteomes; UP000189702; Chromosome 24.
DR GO; GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd17039; Ubl_ubiquitin_like; 1.
DR InterPro; IPR044571; P4KG1-8.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR PANTHER; PTHR45800:SF11; PI3K_PI4K CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:AJR30359.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000189702};
KW Transferase {ECO:0000313|EMBL:AJR30359.1}.
FT DOMAIN 161..457
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
SQ SEQUENCE 641 AA; 72365 MW; 46DBDFB2080DD88A CRC64;
MSRKLDSLVQ TQMAVAVFKS PLRGEYPRNN RMEGKQPVGR RRVFVQTETG CVLGMELDRS
DSAHTVKRRL QVALNFPAEQ SSLTFGDVEL KNDLSAIRND SPLLLTRNYL HRSSSTPCLS
PTGKDLQQRD KSGPIEILGH SDSFNVLKVV VKDIVKAIKM GVDPVPVHSG LGGAYYFRNP
RGENVAIVKP TDEEPFAPNN PKGFVGKALG QPGLKRSVRV GETGFREVVA YLLDHDHFAN
VPPTALVKIT HSVFNVNDGV NRNRPHKNLV SKIASCQQFI RHDFDASDHG TSSFPVSSVH
HIGILDIRIF NTDRHAGNLL VRKLDGIGRF GQMELIPIDH GLCLPETLED PYFEWIHWPQ
ASIPFSEDEL EYIQKLDPMK DCEMLRRELP MIREACLRVL VLCTIFLKEA AAFGLCLAEI
GEMMSREFRA GEEEPSELEV ICLEARRLIA ERELSSPKSD VRDAEFQFDI DFEEPELDLN
PKMATDDFMS RAPFQLGNGF VSNHFPLSKL EECFEEDEEE SEEETEQPCF STFKALERIP
STSKLSMSFK NTSLGDKSQK YSKFSGTKQE NGYLNNSSGH RSANEQLPGN VSFVKLADMN
EEEWNLFLEK FQELLYPGFE KRKSVTLGQK QIQRLGTSCQ F
//
