ID A0A0D3VAL6_9BACL Unreviewed; 876 AA.
AC A0A0D3VAL6;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Cell division protein FtsK {ECO:0000313|EMBL:AJS59110.1};
GN ORFNames=UB51_12310 {ECO:0000313|EMBL:AJS59110.1};
OS Paenibacillus sp. IHBB 10380.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1566358 {ECO:0000313|EMBL:AJS59110.1, ECO:0000313|Proteomes:UP000032320};
RN [1] {ECO:0000313|EMBL:AJS59110.1, ECO:0000313|Proteomes:UP000032320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IHBB 10380 {ECO:0000313|EMBL:AJS59110.1,
RC ECO:0000313|Proteomes:UP000032320};
RX PubMed=25908145;
RA Pal M., Swarnkar M.K., Thakur R., Kiran S., Chhibber S., Singh A.K.,
RA Gulati A.;
RT "Complete Genome Sequence of Paenibacillus sp. Strain IHBB 10380 Using
RT PacBio Single-Molecule Real-Time Sequencing Technology.";
RL Genome Announc. 3:0-0(2015).
CC -!- SUBUNIT: Homohexamer. Forms a ring that surrounds DNA.
CC {ECO:0000256|ARBA:ARBA00025923}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
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DR EMBL; CP010976; AJS59110.1; -; Genomic_DNA.
DR RefSeq; WP_044877535.1; NZ_CP010976.1.
DR AlphaFoldDB; A0A0D3VAL6; -.
DR STRING; 1566358.UB51_12310; -.
DR KEGG; pih:UB51_12310; -.
DR PATRIC; fig|1566358.3.peg.2760; -.
DR HOGENOM; CLU_001981_9_5_9; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000032320; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000313|EMBL:AJS59110.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000032320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 540..730
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 215..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 557..564
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 876 AA; 97255 MW; 5113DC68A00B0B34 CRC64;
MAKRRKKKKA LLSSVLKYEI YGIILITLSV IALSGEATVG WSLSKIFALF LGRFYFVFPL
IGIYFGLMVM INRKWPTRWN SRKSGLVLLV LALTLMSSLS GLEKKLQPIE LNSGSIFKQG
QMDLHEALLS PSVETERSMM DKDIGGGYVG TVQYTVLFWL FGTIGAKLMM IVMFVISFML
ITNLSYIDLI RIVRTKVWKT GSSLTKQFVT HRQSVNQTKS NAKSATVHKS RLLPEDEDEE
DEDFSLPKTK RSTPLFFQLF GSKKKSTRAD TEGQEGSPVI QDQSLIDEDD LEAEEHKHPW
IRAAETKSPE IVATPIIRNF FEQVKSEGMI EEDDLEDVFT GQEVEDLKNV IMNNPDVAAV
GHTRDQDQGD MNKLDDVSTS EVLTSDVDIM PEEPIVQAPP PKPYILPPFR LLAKQQGNGN
SGDQQDYMQT ARKLEATLES FGVRAKVLEV VRGPAVTRYE IQPDIGVKVS RIVSLTDDIA
LALAAKDIRM EAPIPGKSAI GIEVPNNEVS IVTMREVMET SIFQDAESKL SVAFGRDISG
QTIIGNLAKM PHLLVAGATG SGKSVCINGI IASILYKAKP DEVKFLMVDP KMVELNVYNG
IPHLLAPVVT DPKRASLALK KIVVEMEKRY EQFSKSGTRN IEGYNKLMKD NLPAILPYIV
VIVDELADLM MVAANDVEDA ITRLAQMARA AGIHLIIATQ RPSVDVITGV IKANIPSRIA
FGVSSQIDSR TILDMGGAEK LLGRGDMLFL PMGSSKPIRV QGAFINDQEV ENIVDYVRDQ
GQAKYDEFLV PEVEEASANV DEMLDELYDQ AVQIILEAKQ ASVSLLQRRM RVGYTRAARL
IDSMESRGII GPYEGSKPRE VLLSIEQYQQ QNKISS
//
