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Database: UniProt
Entry: A0A0D5ABI1_9NOCA
LinkDB: A0A0D5ABI1_9NOCA
Original site: A0A0D5ABI1_9NOCA 
ID   A0A0D5ABI1_9NOCA        Unreviewed;       730 AA.
AC   A0A0D5ABI1;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   08-MAY-2019, entry version 24.
DE   SubName: Full=Enoyl-CoA hydratase {ECO:0000313|EMBL:AJW40181.1};
GN   ORFNames=NY08_2153 {ECO:0000313|EMBL:AJW40181.1};
OS   Rhodococcus sp. B7740.
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=1564114 {ECO:0000313|EMBL:AJW40181.1, ECO:0000313|Proteomes:UP000032410};
RN   [1] {ECO:0000313|EMBL:AJW40181.1, ECO:0000313|Proteomes:UP000032410}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7740 {ECO:0000313|EMBL:AJW40181.1};
RX   PubMed=25931596;
RA   Zhang D., Li L., Zhu S., Zhang N., Yang J., Ma X., Chen J.;
RT   "Complete Genome Sequence of Rhodococcus sp. B7740, a Carotenoid-
RT   Producing Bacterium Isolated from the Arctic Sea.";
RL   Genome Announc. 3:0-0(2015).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (3S)-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+)
CC         + NADH; Xref=Rhea:RHEA:22432, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57318, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:90726; EC=1.1.1.35;
CC         Evidence={ECO:0000256|SAAS:SAAS01123908};
CC   -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC       {ECO:0000256|SAAS:SAAS00324886}.
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DR   EMBL; CP010797; AJW40181.1; -; Genomic_DNA.
DR   RefSeq; WP_045196211.1; NZ_CP010797.1.
DR   EnsemblBacteria; AJW40181; AJW40181; NY08_2153.
DR   KEGG; rhb:NY08_2153; -.
DR   PATRIC; fig|1564114.4.peg.2114; -.
DR   KO; K01782; -.
DR   OrthoDB; 977512at2; -.
DR   UniPathway; UPA00659; -.
DR   Proteomes; UP000032410; Chromosome.
DR   GO; GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   SUPFAM; SSF52096; SSF52096; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032410};
KW   Fatty acid metabolism {ECO:0000256|SAAS:SAAS00324839};
KW   Lipid metabolism {ECO:0000256|SAAS:SAAS00324863};
KW   NAD {ECO:0000256|SAAS:SAAS00830857};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00331296};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032410}.
FT   DOMAIN      326    504       3HCDH_N. {ECO:0000259|Pfam:PF02737}.
FT   DOMAIN      507    607       3HCDH. {ECO:0000259|Pfam:PF00725}.
FT   COILED       86    106       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   730 AA;  77290 MW;  8C0A0602B616DB80 CRC64;
     MSENMIGWER GADGIVVLTM DDAGKSANTM NDTYIASMAA AVERLEAEKD DITGVVITSA
     KKSFFAGGDL DDMTKDPGAV DERDVARALT ERIDGIKKVL RRLETLGRPV VAALNGAALG
     GGFEIALHTH HRIAADVPGN RIGLPEATLG LLPGGGGIVR TVRLMGLDAA LSKVLTKGQQ
     HSVADAMTLG LIDATVTGVA ELIPAAKAWI AENPSAVQPW DVKGFEIPGG GPTDPAVAQN
     LLAATALLRR QLKGAPSPAP RAILAAAAEC ASVDVDTADR IETRYFVSLM TDRVAQNMIR
     AFFFDMQTIR RGTSRPAGHD TFTARTVAVI GAGMMGGAIA YVCAKAGIEV VLKDLDRDAA
     DRGKQYAEKL EAKALERGST TAERSAALLD RIRPTADATD CAAVDLVIEA AFESVDVKNR
     VFAELGGVVP AEVVLGSNTS QLPISILADG VSRPENFIGI HFFSPADKMP LVEIIRGRAT
     SDSTVAKVVD FVFQIGKTPI VVNDSRGFFT SRVIGAFLDE AMAAVGEGVN PVFVEQAGAQ
     AGYPVPPLQL MDQVTLSLSQ KIRKENERAL ASEGSPPRRH GSDAVMDRMV DELHRPGRAG
     GGGFYSYDES GARAGIWPGV RTSFDSGSTR IPFVDMQERM LFAEAIEAVK CLDEGVLTSV
     ADANIGSLLG IGFPPWTGGV IQYIDQYDGG LSGFVDRARE LASKYGAHFE PPQSLVNKAL
     RGERVHTLVS
//
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