ID A0A0D5AH63_9NOCA Unreviewed; 1456 AA.
AC A0A0D5AH63;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:AJW42138.1};
GN ORFNames=NY08_4133 {ECO:0000313|EMBL:AJW42138.1};
OS Rhodococcus sp. B7740.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1564114 {ECO:0000313|EMBL:AJW42138.1, ECO:0000313|Proteomes:UP000032410};
RN [1] {ECO:0000313|EMBL:AJW42138.1, ECO:0000313|Proteomes:UP000032410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7740 {ECO:0000313|EMBL:AJW42138.1};
RX PubMed=25931596;
RA Zhang D., Li L., Zhu S., Zhang N., Yang J., Ma X., Chen J.;
RT "Complete Genome Sequence of Rhodococcus sp. B7740, a Carotenoid-Producing
RT Bacterium Isolated from the Arctic Sea.";
RL Genome Announc. 3:0-0(2015).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; CP010797; AJW42138.1; -; Genomic_DNA.
DR RefSeq; WP_045198260.1; NZ_CP010797.1.
DR STRING; 1564114.NY08_4133; -.
DR KEGG; rhb:NY08_4133; -.
DR PATRIC; fig|1564114.4.peg.4077; -.
DR HOGENOM; CLU_000022_51_2_11; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000032410; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 931..1006
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1456 AA; 156157 MW; 8C1AB6720884AB71 CRC64;
MFDDLPLTSS QADIWLAQQF MPDVPFAIAY YVDIVGTVNV DTLAASGSTA HREFSSSTMR
IAEVDGIPVQ RFVDADTEAV EILDLREHER PEEAARQWMN DDCRTPFSMD GQLVRLRVLR
VGDDRVFWYT RAHHIALDGY ASMKVLERAA TLYSAMLGGV QPEPIDATSP AELLAEDERY
RTSTRARRDR AHWASADLGY GAPWGRSAQP ASEPIVVGED RSISRTASGR ATSTVVIAAF
AAYLARMNDA DDVDLSLPVS ARPTALLRRA GSSLSHMVPL RLPGVGSATV NNVVKSAEVA
IGAVLRHQRS RPPVSESGHA VRAGRFGPTI NVMMFANTVA VGDFDGEIDI LTTGPVSDLA
VNIYPGRGGE RPRIAFEANS NVYTPSDLAR RHERFLRFLD LFADSGCGDT AVADLDLFLP
EEPRATPASV GAASAEPGSL NDVFSTVITQ HGNRIAIQDG EVSVTYAELD TRVAALASAL
TARGIGTEDR VAVRIGRSVE GVVAFWAIAR VGAVYVPVDP GHPRERAEFV MRDSGAVLGL
CSGGGQFGEV EWLDLDDVLA ESGPGDESTP TAPHRAAYVI YTSGSTGTPK GVVVTHDGIA
ALVQQIRSSY DLDVESRVCH LASPGFDTAI VEVLAAATAG AAVVIAPPDS YGGAELSELI
ARQAITHLLI TPSALATLDP AALAGVGTIV IGGEAAPQDT VDRWSVDRRL FNAYGPTETT
CSVTMTVPLN PGSAYGIGRA MVGAVIHLLD RTLRPVPPGA VGEIYIETLG VARGYLGRTP
DTAARFVANP FGSAGLRMFR SGYRARLRGD GTLEFLGRSD DQIKIRGNRV ELGEIDAALR
SLPEVAAASS ALRRSRTGDA RIDGYVVAGR SEQVLDTERI RRDLAGRLPA HMVPATISIL
DEIPLTLNRK VDRGALPVPS PTARSTGTPI EPSGATEEMV AAAFARILGR DGIDCAASFF
DLGGDSLAAT RVVGSVRAEA SVEIGVRDLA EAPSVRALAA RIDARRLRGL QQDSRPEAGT
SGGVAAIPLA PQQRHIDRSA PLPLYNLPFS VTISGRFHGE VAVEALTDLI GRHSTLRTRY
PDVDGSPAQV VEPNCAVAEV NLDVVDFDDA AMWDTLERPF DVRTEFPIRA RLFAVAPDRH
VLACAVHHSA ADGWSLGLLA SDFVLAYHAR IAGTAPSWPE LPLQYADYSV WAADRDVSAD
LDFWRTELAD MPSSRGLPLD RPRRQEWDFT GSRTSLRFDA DATERMSDLA QRCGTGRFTV
LRAALLILLA ETTKSTDLVV GTPVAGRDDP RLEQLVGTFT NSVAIRTDIG SATSVEDVVQ
SARASELRAF DHASVPFEDV VAHLGAQSTE ARHPIFQVAL SLDVFTAAAF DVGDVRFEIT
PRPLDIAKCD LHFHVTEHRD SEGEAIETSV DIVYPTTLFD ADTALELSRC FERIVHAMIA
APDSAWRDLL AIEPPT
//
