ID A0A0D5AI81_9NOCA Unreviewed; 949 AA.
AC A0A0D5AI81;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Na(+) H(+) antiporter subunit A Na(+) H(+) antiporter subunit B {ECO:0000313|EMBL:AJW42581.1};
GN ORFNames=NY08_4581 {ECO:0000313|EMBL:AJW42581.1};
OS Rhodococcus sp. B7740.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=1564114 {ECO:0000313|EMBL:AJW42581.1, ECO:0000313|Proteomes:UP000032410};
RN [1] {ECO:0000313|EMBL:AJW42581.1, ECO:0000313|Proteomes:UP000032410}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7740 {ECO:0000313|EMBL:AJW42581.1};
RX PubMed=25931596;
RA Zhang D., Li L., Zhu S., Zhang N., Yang J., Ma X., Chen J.;
RT "Complete Genome Sequence of Rhodococcus sp. B7740, a Carotenoid-Producing
RT Bacterium Isolated from the Arctic Sea.";
RL Genome Announc. 3:0-0(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP010797; AJW42581.1; -; Genomic_DNA.
DR RefSeq; WP_045198746.1; NZ_CP010797.1.
DR AlphaFoldDB; A0A0D5AI81; -.
DR STRING; 1564114.NY08_4581; -.
DR KEGG; rhb:NY08_4581; -.
DR PATRIC; fig|1564114.4.peg.4524; -.
DR HOGENOM; CLU_007100_2_0_11; -.
DR Proteomes; UP000032410; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 100..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 496..516
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 560..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 594..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..637
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 682..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 800..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 827..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 865..885
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 905..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 57..97
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 120..403
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 602..666
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 682..760
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 801..923
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 949 AA; 99842 MW; FBF8F2929C58CE93 CRC64;
MLAILLAHAA AALLAPLLVR WWGRNAFFPL ALVPALSLIW VSGNWNTDQK LSIEWVPGLS
MNIDMRFDSL AAIMSLLVLG IGALILLYCA RYFEDDEPRL GLFAAEMVAF SGAMFGLITS
DNMLVLYIFW EITTVLSFLL VGHYAERASS RRAATQALLV TTAGGLAMLV GIIILGQVSG
TYNLSELVAN APGGWLPGVA IVLVLIGALS KSAIVPLHFW LPGAMAAPTP VSGYLHAAAM
VKAGIYLVAR LAPGFADSGP WRATVISLGL LSMILAGWRA LRAFDLKLIL AFGTVSQLGF
LMVLVGIGSE KAMLAGLTMV IAHAMFKAAL FMVVGIVDHT TGTRDIRKLA HLGKKAPWLA
AIAALAAASM AGLPPMLGFV GKETALSAVI STPTLDPVVA AVVVAGLVIG SILTVTYSIR
FVWGAFARKQ LKRPSPSVRA MHAPSALFLA APAFLAVLGV IAGFGSSIVD RIVSPYARTL
PSYGQEPYHL ALWHGFNLPL ALTVVVVTGG VGLFIAHRVV NRLKFEHPPL GNADRIYDNV
LKYMDALSIR LTGTTQRGSL PLTQGTILLT LVLLPMIVLL VGQDSGLDYT LWNTPLQLVI
GVIMIAGGLG ATVMRNRLAS VILVGLTGYG CGVIFAIHGA PDLALTQFLV ETLTLVVFVL
VLRKLPAEVD DRGSAGSRGP RAVLAVAVGA TVSVLGAFAM NARNTAPVSL LLPDAAYDLG
DGKNVINVIL VDIRAWDTLG EICVLLVAAT GVASLVFRNR RFGSAPRVSD APASSSDANF
AAETTWLLGG DLIDPRHRSL ILEVTTRLIF PTIMVLSIYF FFSGHNAPGG GFAGGLTAGL
ALVLRYLAGG RYELGEAVPI DAGKILGLGL IFAAGTAVAS MFLGAPALSS ATLEVTLPIL
GDIKLVTALF FDLGVYLIVV GLVLDVLRSL GARLDAQVEM QSQGRVSAP
//
