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Database: UniProt
Entry: A0A0D5NIS6_9BACL
LinkDB: A0A0D5NIS6_9BACL
Original site: A0A0D5NIS6_9BACL 
ID   A0A0D5NIS6_9BACL        Unreviewed;       450 AA.
AC   A0A0D5NIS6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=VN24_10195 {ECO:0000313|EMBL:AJY74892.1};
OS   Paenibacillus beijingensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Paenibacillus.
OX   NCBI_TaxID=1126833 {ECO:0000313|EMBL:AJY74892.1, ECO:0000313|Proteomes:UP000032633};
RN   [1] {ECO:0000313|EMBL:AJY74892.1, ECO:0000313|Proteomes:UP000032633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24997 {ECO:0000313|EMBL:AJY74892.1,
RC   ECO:0000313|Proteomes:UP000032633};
RX   PubMed=25937453; DOI=10.1016/j.jbiotec.2015.04.015;
RA   Kwak Y., Shin J.H.;
RT   "Complete genome sequence of Paenibacillus beijingensis 7188(T) (=DSM
RT   24997(T)), a novel rhizobacterium from jujube garden soil.";
RL   J. Biotechnol. 206:75-76(2015).
RN   [2] {ECO:0000313|Proteomes:UP000032633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24997 {ECO:0000313|Proteomes:UP000032633};
RA   Kwak Y., Shin J.-H.;
RT   "Genome sequence of Paenibacillus beijingensis strain DSM 24997T.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP011058; AJY74892.1; -; Genomic_DNA.
DR   RefSeq; WP_045670325.1; NZ_CP011058.1.
DR   EnsemblBacteria; AJY74892; AJY74892; VN24_10195.
DR   KEGG; pbj:VN24_10195; -.
DR   PATRIC; fig|1126833.4.peg.2252; -.
DR   KO; K02313; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000032633; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032633};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032633}.
FT   DOMAIN      144    272       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      356    425       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     152    159       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   450 AA;  51283 MW;  739A078BF40C193B CRC64;
     MDSHTHDLWQ QVLSIIQTKL SKPSFDTWFK ATKASFADDS LLVVTAPTTF AVEWLESRYT
     KLVRSTVFDY LGRTVDIKFV IEENRPPEPA APMPTVIVPT QAAQEEPFSH MLNPKYVFDT
     FVIGANNRFA HAASLAVAEA PAKAYNPLFL YGGVGLGKTH LMHAIGHYIL EHNPSTKVMY
     ISSEKFTNEF INAIRDNRGE SFRNKYRNID VLLIDDIQFL AGKDGTQEEF FHTFNALHEE
     RKQIVISSDR TPKEIPTLEE RLRSRFEWGL ITDIQPPDLE TRIAILRKKA KAENLDIPNE
     AMAYIANQID TNIRELEGAL IRVVAYSSLI NEDISAHLAA EALKDIIPSS RPKMITIQDI
     QQKVGEFYGL RLDEFKARKR TKAVAYPRQI AMYLSRELTD YSLPKIGEAF GGRDHTTVIH
     AHEKITQQLK IDQDLFKIIQ NLTDKVKNHT
//
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