ID A0A0D5NP82_9BACL Unreviewed; 971 AA.
AC A0A0D5NP82;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN ORFNames=VN24_24255 {ECO:0000313|EMBL:AJY77091.1};
OS Paenibacillus beijingensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1126833 {ECO:0000313|EMBL:AJY77091.1, ECO:0000313|Proteomes:UP000032633};
RN [1] {ECO:0000313|EMBL:AJY77091.1, ECO:0000313|Proteomes:UP000032633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24997 {ECO:0000313|EMBL:AJY77091.1,
RC ECO:0000313|Proteomes:UP000032633};
RX PubMed=25937453; DOI=10.1016/j.jbiotec.2015.04.015;
RA Kwak Y., Shin J.H.;
RT "Complete genome sequence of Paenibacillus beijingensis 7188(T) (=DSM
RT 24997(T)), a novel rhizobacterium from jujube garden soil.";
RL J. Biotechnol. 206:75-76(2015).
RN [2] {ECO:0000313|Proteomes:UP000032633}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24997 {ECO:0000313|Proteomes:UP000032633};
RA Kwak Y., Shin J.-H.;
RT "Genome sequence of Paenibacillus beijingensis strain DSM 24997T.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CP011058; AJY77091.1; -; Genomic_DNA.
DR RefSeq; WP_045672516.1; NZ_CP011058.1.
DR AlphaFoldDB; A0A0D5NP82; -.
DR STRING; 1126833.VN24_24255; -.
DR KEGG; pbj:VN24_24255; -.
DR PATRIC; fig|1126833.4.peg.5335; -.
DR HOGENOM; CLU_002472_1_3_9; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000032633; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000032633}.
FT DOMAIN 685..701
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 611..618
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 971 AA; 106365 MW; F4D9A0BD662F8929 CRC64;
MASYTPMIEQ YLAVKEEAKD AFLFFRLGDF YELFFQDAVL AARELDITLT GRAGGAEEKI
PMCGVPYHSA DNYIARLIEK GYKVAICEQV EDPAAAKGVV RREIVRVVTP GTVMESKSLT
DEANNFIVSA AAEGASYAIA ACDLTTGELY VTSCEESFDP LVDELGVYHP AEIVTEAAMT
EQLRNRTASW NRLVLLSERA PMDKDRLEAH FSEDQLSGLA AIRVKAVALL LAYLDETQKR
SLAHVRSVRS YEPSHYLVLD PFTRRNLELT ETVQSRSKKG SLLWLLDKTE TSMGARLLRR
WIDKPLLSRD PVEKRLEAVD KLCSDLILRE DVRRELDGIY DLERLVGRVA FGSANGRDLN
ALKQSLRHVP ALRELCAVSG SATLAALVAR IDDCRDLADT IETVVIDDPP VSVRDGGLIR
SGYDEYLDRL RGASTDGKKW LADLERRERE ATGIKSLKIG YNKVFGYFLE VSKANLSLLP
EGRYERKQTL ANAERFVTPE LKEKERLILE AEEKMVDVEY RIFMELRDHL ASQLHRLQKL
AEMIATLDAL QSLATVSAER RYVKPQLTDG YDLIVEQGRH PVVEAVMEGK PFIANGTALT
AEEASMLLIT GPNMAGKSTY MRQVALICIM AQIGCFVPAK SAVVPLLDRI FTRIGAADDL
IGGQSTFMVE MKDIQIMTSK ATPRSLVIID ELGRGTSTAE GMSIAQAVIE YVHHRIGCKA
LVSTHFHELA HLEETLPKLR NACMAVRESD GDVTFLRRLV PGAASTSYGI YCARLAGLPE
RIIDRAYELL EDANAGHASD AAIDEAEGTD GETAARKQPA YAGAASGALL QGSAAREASA
AAEDAATAAS GKSGSHDAYE PGYSRDPQLA QAIAADRTAA TETSAIKETA AGPESYAMKE
TAAAAGAERS GEIVQLSIFD DPALTELSVS KRRGSAKAEQ LAEGLRKLDL LNMTPLQAIQ
WLSDMKSKLA E
//
